Serotonin is a naturally occurring vasoactive substance that has diverse cardio-
physiological effects. These effects can be explained by the existence of serotonin receptor …

Serotonin, or 5‐hydroxytryptamine, is a naturally‐occurring vasoactive substance found
primarily in the brain, enterochromaffin tissue, and blood platelets. It has diffuse …

The effects of serotonin (5-hydroxytrypta-mine; 5-HT) on the cardiovascular system are
complex. These effects, consisting of bradycardia or tachycardia, hypotension or …

The cardiovascular actions of serotonin and its antagonists are reviewed with a view to
clarifying whether serotonin has a role in blood pressure control through actions on the …

The present article deals with the pathophysiological role of serotonin in cardiovascular
disease and in other disorders that are accompanied by cardiovascular pathophysiological …

Serotonin exerts complex effects in the cardiovascular system, including hypotension or
hypertension, vasodilatation or vasoconstriction, and/or bradycardia or tachycardia; the …

Serotonergic receptors have been identified in the blood vessels of the heart and in
myocardial tissue. We indirectly examined the potential significance of these receptors by …

Aggregating platelets release serotonin, which induces contraction of most vascular smooth
muscle by activation of S2-serotoninergic receptors. Serotonin released in the circulation …

Introduction Inhibitory effects of serotoninlA receptor agonists Studies of the site and
mechanism of the sympatholytic effect of serotoninlA receptor agonists Studies of the …

5-Hydroxytryptamine (5-HT; serotonin) was discovered more than 60 years ago as a
substance isolated from blood. The neural effects of 5-HT have been well investigated and …