Serotonin and the heart
WH Frishman, P Grewall - Annals of medicine, 2000 - Taylor & Francis
Serotonin is a naturally occurring vasoactive substance that has diverse cardio-
physiological effects. These effects can be explained by the existence of serotonin receptor …
physiological effects. These effects can be explained by the existence of serotonin receptor …
Serotonin and serotonin antagonism in cardiovascular and non‐cardiovascular disease
WH Frishman, S Huberfeld, S Okin… - The Journal of …, 1995 - Wiley Online Library
Serotonin, or 5‐hydroxytryptamine, is a naturally‐occurring vasoactive substance found
primarily in the brain, enterochromaffin tissue, and blood platelets. It has diffuse …
primarily in the brain, enterochromaffin tissue, and blood platelets. It has diffuse …
Serotonin (5Ht) and its antagonists: involvement in the cardiov ascular system
JF Marwood, GS Stokes - Clinical and experimental …, 1984 - Wiley Online Library
The cardiovascular actions of serotonin and its antagonists are reviewed with a view to
clarifying whether serotonin has a role in blood pressure control through actions on the …
clarifying whether serotonin has a role in blood pressure control through actions on the …
Cardiovascular effects of serotonin agonists and antagonists
PR Saxena, CM Villaló - Journal of cardiovascular pharmacology, 1990 - journals.lww.com
The effects of serotonin (5-hydroxytrypta-mine; 5-HT) on the cardiovascular system are
complex. These effects, consisting of bradycardia or tachycardia, hypotension or …
complex. These effects, consisting of bradycardia or tachycardia, hypotension or …
Cardiovascular effects of serotonin
PM Vanhoutte - Journal of cardiovascular pharmacology, 1987 - journals.lww.com
The major target for circulating serotonin (released from aggregating platelets) appears to
be the blood vessel wall (although little evidence is available), suggesting a role for the …
be the blood vessel wall (although little evidence is available), suggesting a role for the …
Pathophysiological relevance of serotonin
PA Van Zwieten - Journal of Cardiovascular Pharmacology, 1987 - journals.lww.com
The present article deals with the pathophysiological role of serotonin in cardiovascular
disease and in other disorders that are accompanied by cardiovascular pathophysiological …
disease and in other disorders that are accompanied by cardiovascular pathophysiological …
Serotonin receptors as cardiovascular targets
CM Villalón, P de Vries, PR Saxena - Drug Discovery Today, 1997 - Elsevier
Serotonin exerts complex effects in the cardiovascular system, including hypotension or
hypertension, vasodilatation or vasoconstriction, and/or bradycardia or tachycardia; the …
hypertension, vasodilatation or vasoconstriction, and/or bradycardia or tachycardia; the …
Serotonin and the heart: effects of ketanserin on myocardial function, heart rate, and arrhythmias
S Saman, F Thandroyen, LH Opie - Journal of Cardiovascular …, 1985 - journals.lww.com
Serotonergic receptors have been identified in the blood vessels of the heart and in
myocardial tissue. We indirectly examined the potential significance of these receptors by …
myocardial tissue. We indirectly examined the potential significance of these receptors by …
Serotoninergic mechanisms in hypertension. Focus on the effects of ketanserin.
P Vanhoutte, A Amery, W Birkenhäger… - …, 1988 - Am Heart Assoc
Aggregating platelets release serotonin, which induces contraction of most vascular smooth
muscle by activation of S2-serotoninergic receptors. Serotonin released in the circulation …
muscle by activation of S2-serotoninergic receptors. Serotonin released in the circulation …
[引用][C] Role of serotonin1A and serotonin2 receptors in the central regulation of the cardiovascular system.
RB McCALL, ME Clement - Pharmacological reviews, 1994 - ASPET
Introduction Inhibitory effects of serotoninlA receptor agonists Studies of the site and
mechanism of the sympatholytic effect of serotoninlA receptor agonists Studies of the …
mechanism of the sympatholytic effect of serotoninlA receptor agonists Studies of the …