Glypican 3 expression in pediatric malignant solid tumors
Y Kinoshita, S Tanaka, R Souzaki… - European Journal of …, 2015 - thieme-connect.com
Purpose Glypican 3 (GPC3) is one of the cell surface heparan sulfate proteoglycans that
binds to the cell membrane, and it is known as an oncofetal protein in adult malignant …
binds to the cell membrane, and it is known as an oncofetal protein in adult malignant …
Expression of glypican-3 in undifferentiated embryonal sarcoma and mesenchymal hamartoma of the liver
M Levy, A Trivedi, J Zhang, L Miles, AN Mattis, GE Kim… - Human pathology, 2012 - Elsevier
Glypican-3 (GPC3) is an oncofetal protein that has been demonstrated to be a useful
diagnostic immunomarker for hepatocellular carcinoma and hepatoblastoma. Its expression …
diagnostic immunomarker for hepatocellular carcinoma and hepatoblastoma. Its expression …
Expression of glypican 3 in hepatoblastoma: an immunohistochemical study of 65 cases
DL Zynger, A Gupta, C Luan, PM Chou, GY Yang… - Human pathology, 2008 - Elsevier
Glypican 3 is a heparin sulfate proteoglycan bound to the cell surface that is theorized to
participate in cell signaling, resulting in embryonic cell growth and differentiation. The GPC3 …
participate in cell signaling, resulting in embryonic cell growth and differentiation. The GPC3 …
[HTML][HTML] Glypican-3 is a prognostic factor and an immunotherapeutic target in hepatocellular carcinoma
Y Haruyama, H Kataoka - World journal of gastroenterology, 2016 - ncbi.nlm.nih.gov
Abstract Glypican-3 (GPC3) is a cell surface oncofetal proteoglycan that is anchored by
glycosylphosphatidylinositol. Whereas GPC3 is abundant in fetal liver, its expression is …
glycosylphosphatidylinositol. Whereas GPC3 is abundant in fetal liver, its expression is …
Glypican 3 overexpression in primary and metastatic Wilms tumors
M Tretiakova, DL Zynger, C Luan, NK Andeen, LS Finn… - Virchows Archiv, 2015 - Springer
Abstract Glypican 3 (GPC3), a heparan sulfate proteoglycan, plays a role in cell growth and
differentiation. Mutations of the GPC3 gene are responsible for Simpson-Golabi-Behmel …
differentiation. Mutations of the GPC3 gene are responsible for Simpson-Golabi-Behmel …
Phase I study of glypican-3-derived peptide vaccine therapy for patients with refractory pediatric solid tumors
N Tsuchiya, A Hosono, T Yoshikawa, K Shoda… - …, 2018 - Taylor & Francis
The carcinoembryonic antigen glypican-3 (GPC3) is a good target of anticancer
immunotherapy against pediatric solid tumors expressing GPC3. In this non-randomized …
immunotherapy against pediatric solid tumors expressing GPC3. In this non-randomized …
The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma
N Yamauchi, A Watanabe, M Hishinuma, K Ohashi… - Modern …, 2005 - nature.com
Expression profiling of hepatocellular carcinoma has demonstrated that glypican 3 (GPC3),
a heparan sulfate proteoglycan anchored to the membrane, is expressed at a markedly …
a heparan sulfate proteoglycan anchored to the membrane, is expressed at a markedly …
Next-generation cancer immunotherapy targeting glypican-3
Y Shimizu, T Suzuki, T Yoshikawa, I Endo… - Frontiers in …, 2019 - frontiersin.org
Glypican-3 (GPC3), a 65 kD protein consisting of 580 amino acids, is a heparan sulfate
proteoglycan bound to the cell membrane by glycosylphosphatidylinositol. This protein is …
proteoglycan bound to the cell membrane by glycosylphosphatidylinositol. This protein is …
Immunohistochemical expression of glypican-3 in pediatric tumors: an analysis of 414 cases
ES Chan, BR Pawel, DA Corao… - Pediatric and …, 2013 - journals.sagepub.com
Glypican-3 (GPC3) is a proteoglycan thought to play an important role during development.
Germline GPC3 mutations are seen in the rare Simpson-Golabi-Behmel syndrome (SGBS) …
Germline GPC3 mutations are seen in the rare Simpson-Golabi-Behmel syndrome (SGBS) …
Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker
T Nakatsura, Y Yoshitake, S Senju, M Monji… - Biochemical and …, 2003 - Elsevier
With the global pandemic of hepatitis B and C infections, the incidence of Hepatocellular
carcinoma (HCC) is rapidly increasing world wide. We identified glypican-3 (GPC3), a novel …
carcinoma (HCC) is rapidly increasing world wide. We identified glypican-3 (GPC3), a novel …