In order to investigate the effect of chitosan/pshRNA plasmid nanoparticles targeting MDR1
genes on the resistance of A2780/TS cells to paclitaxel, chitosan/pshRNA plasmid …

Nanoparticle drug delivery system (NDDS) is quite different from the widely studied
traditional chemotherapy which suffers from drug resistance and side effect. NDDS offers the …

Ovarian cancer (OC) has a low five-year survival rate, mainly because of its drug resistance
to chemotherapy. It is the key to reverse drug resistance to combine multiple sensitization …

We have designed and developed an effective drug delivery system using biocompatible
polymer of poly (ethylene glycol)-polyaspartic acid (mPEG-PAsp) for co-loading the …

To test the ability of nanoparticle formulations to overcome P-glycoprotein (P-gp)–mediated
multidrug resistance, several different doxorubicin and paclitaxel-loaded lipid nanoparticles …

Objectives: Ovarian cancer has the highest mortality of all the gynecologic cancers. The
antitumor agent paclitaxel has been proved to be efficient in the treatment of ovarian cancer …

Simple Summary Ovarian cancer (OvCa) is a prominent cause of cancer death in women
due to missed early signs and late diagnoses. Once a woman is diagnosed with OvCa, the …

Development of resistance toward anticancer drugs results in ineffective therapy leading to
increased mortality. Therefore, overriding resistance and restoring sensitivity to anticancer …

Two types of nanoparticles were prepared using the diblock copolymer methoxy poly
(ethylene glycol)-block-poly (caprolactone)(MePEG-b-PCL), with either a short PCL block …

Ovarian cancer is the most lethal gynecological cancer of female reproductive system. In
order to improve the survival rate, some modifications on nanoparticles surfaces have been …