Background The aims of this study were to prepare the collagen-poly (3-
acrylamidophenylboronic acid) nanoparticles (collagen-PAPBA NPs) encapsulating …

Background Platinum resistance is a major challenge in the management of ovarian cancer.
Even low levels of acquired resistance at the cellular level lead to impaired response to …

Co-encapsulated doxorubicin (DOX) and curcumin (CUR) in poly (butyl cyanoacrylate)
nanoparticles (PBCA-NPs) were prepared with emulsion polymerization and interfacial …

Background Cisplatin (CSP) is a potent anticancer drug widely used in treating glioblastoma
multiforme (GBM). However, CSP's clinical efficacy in GBM contrasted with low therapeutic …

Background Poly (L-γ-glutamylglutamine) paclitaxel (PGG-PTX) conjugate is a non-diblock
polymeric drug nanoparticle intended to improve the therapeutic index of paclitaxel. The …

Objective: The present article aimed to enhance the therapeutic efficacy of carboplatin (CP)
using the formulation of chitosan-poly (lactic glycolic acid) nanoparticles (CS-PLGA NPs) …

The power of tumorigenesis, chemo-resistance and metastasis in malignant ovarian tumors
resides in a tiny population of cancer cells known as ovarian cancer stem cells (OCSCs) …

Ovarian carcinoma is one of the most common cancers among women. The most common
type of ovarian cancer is epithelial ovarian cancer and cisplatin (DDP) is one of the most …

Paclitaxel is a microtubule inhibitor causing mitotic arrest and is widely used in cancer
chemotherapy. However, its poor water solubility restricts its direct clinical applications. In …

Carboplatin is a platinum based drug used in the treatment of several malignancies. Due to
poor cellular uptake, generally, a larger dose of drug is administered to achieve therapeutic …