Goal: This work presents the development of a Hybrid Mock Circulatory Loop (HMCL) to
simulate hemodynamics at patient-specific level in terms of both 3D geometry and …

Mechanical hemolysis is a major concern in the design of cardiovascular devices, such as
prosthetic heart valves and ventricular assist devices. The primary cause of mechanical …

The liver is organized in hexagonal functional units–termed lobules–characterized by a
rather peculiar blood microcirculation, due to the presence of a tangled network of …

Understanding the mechanical properties of human liver is the most critical aspect of
numerical modeling for medical applications and impact biomechanics. Many researchers …

BACKGROUND & AIMS: The aim of this study was to identify protective mechanisms of cold
machine perfusion in liver grafts donated after cardiac death. METHODS: Pig livers exposed …

This work focuses on the direct numerical simulation of the pulsatile flow through a bileaflet
mechanical heart valve under physiological conditions and in a realistic aortic root …

We propose a mesh-free and discrete (particle-based) multi-physics approach for modelling
the hydrodynamics in flexible biological valves. In the first part of this study, the method is …

Hydraulic models of circulation are used to test mechanical heart assist devices and for
research and training purposes. However, when compared with numerical models, they are …

The liver function may be degraded after partial liver ablation surgery. Adverse liver
hemodynamics have been shown to be associated to liver failure. The link between these …

This review focuses on the application of hypothermic perfusion technology as a topic of
current interest with the potential to have a salutary impact on the mounting clinical …