Compared to experiments involving pigs, cows and/or sheep, transgenesis applied to goats
is probably less advertised. However, recent successes and increasing amount of dedicated …

Until recently, precise modification of the animal genome by gene targeting was restricted to
the mouse because germline competent embryonic stem cells are not available in any other …

Genome editing is, by definition, the manipulation of the genetic material of an animal by
deleting, replacing, or inserting a DNA sequence. There are three types of “genome editors,” …

Knock-in mice are useful for evaluating endogenous gene expressions and functions in vivo.
Instead of the conventional gene-targeting method using embryonic stem cells, an …

The first 2019 international symposium of molecular design breeding in animals was held on
19th September, at Northwest A&F University in Yangling, the historic cradle of innovation …

Genome editing is a precise modification of the genome in many organisms using
engineered nucleases as an emerging and powerful technique. All genome editing tools are …

Highlights•Genetic improvement decreases the environmental footprint of animal-source
protein.•New breeding methods enable precise intraspecies and interspecies allele …

Transgenic technology has been applied mainly in the study of gene structure and function
in model organisms and gene therapy for human diseases. Transgenic technology has …

We are witnessing the timely convergence of several technologies that together will have
significant impact on research, human health and in animal and plant breeding. The …

Genome editing in large animals has tremendous practical applications, from more accurate
models for medical research through improved animal welfare and production efficiency …