The objective was to determine the progression of nervous system involvement in
spinocerebellar ataxia type 1 (SCA1). Three presymptomatic members of an Italian SCA1 …

Although ataxia is by definition the prominent symptom of ataxia disorders, there are various
neurological signs that may accompany ataxia in affected patients. Reliable and quantitative …

Spinocerebellar ataxias (SCAs) constitute a heterogeneous group of neurodegenerative
diseases characterized by progressive cerebellar ataxia in association with some or all of …

Abstract Spinocerebellar ataxias type 1 (SCA1) is an autosomal dominant disease usually
manifesting in adulthood. We performed a prospective 1-year longitudinal study in 14 …

To evaluate the psychological consequences of genetic testing for spinocerebellar ataxia
(SCA), state and trait anxiety inventories (SAI and TAI) and social desirability scale (SDS) …

This is one of the first studies assessing the pattern of cognitive impairment in
spinocerebellar ataxia 2 (SCA2). Cognitive function was studied in 17 patients with …

Background The spinocerebellar ataxias (SCA) are a heterogeneous group of progressive
neurodegenerative disorders that are associated with diffuse cerebellar atrophy. While the …

Several authors have recently reported a broad cognitive impairment in autosomal dominant
cerebellar ataxias (ADCAs) patients. However, only a few studies on neuropsychological …

Objectives–Frequency and distribution of dominant ataxias caused by dynamic mutations
may vary in different populations, which has been explained on the basis of relative …

Objective: To obtain quantitative data on the progression of the most common
spinocerebellar ataxias (SCAs) and identify factors that influence their progression, we …