Objectives To describe and correlate the genotype and phenotype of patients diagnosed
with SCAs in southern of Brazil. Patients and methods Data were collected from the records …

Introduction Cognitive impairment (CI) is reported but is poorly explored in spinocerebellar
ataxia 2 (SCA2). This study was undertaken to evaluate and classify cognitive impairment in …

Objectives: Our study attempted to systematically explore the prevalence of extra-cerebellar
signs and non-motor symptoms, such as anxiety, depression, fatigue, excessive daytime …

Objectives To evaluate disease progression and determine validity of clinical tools for
therapeutic trials. Design Prospective cohort study (36 months). Setting Referral center …

Introduction Cognitive impairment has now been recognised to be present in patients with
several of spinocerebellar ataxias (SCAs). Cognitive impairment in patients with …

Autosomal dominant cerebellar ataxia type 1 (ADCA1) is a clinical and genetic
heterogeneous neurodegenerative disorder which leads to progressive cerebellar ataxia …

The spinocerebellar ataxias (SCAs) are clinically and genetically a heterogeneous group of
neurodegenerative disorders. To date, eight different loci causing SCA have been identified …

The prodromal phase of spinocerebellar ataxias (SCAs) has not been systematically
studied. Main findings come from a homogeneous SCA type 2 (SCA2) population living in …

During recent decades, many studies have yielded evidence for cerebellar involvement in
cognitive, emotional and affective processes besides the well-known cerebellar contribution …

Purpose To determine cognitive impairment patterns in patients with spinocerebellar ataxia
type 6 (SCA6) compared to patients with idiopathic late-onset cerebellar ataxia (ILOCA) …