Treatment of hypertension in the elderly: II. Cognitive and behavioral function. Results of a Department of Veterans Affairs Cooperative Study.

G Goldstein, BJ Materson, WC Cushman, DJ Reda… - …, 1990 - Am Heart Assoc
This study was designed to determine whether blood pressure reduction, per se, causes
adverse effects on cognitive and behavioral function in elderly hypertensive patients. Men …

Treating hypertension in the older person: an evaluation of the association of blood pressure level and its reduction with cognitive performance

AS Bird, RA Blizard, AH Mann - Journal of hypertension, 1990 - journals.lww.com
No adverse effect upon cognitive function has been detected during the first 9 months of
treatment by a thiazide diuretic (Moduretic; Merck Sharp & Dohme, Hoddesdon, UK) or a …

Treatment of hypertension in the elderly: I. Blood pressure and clinical changes. Results of a Department of Veterans Affairs Cooperative Study.

BJ Materson, WC Cushman, G Goldstein, DJ Reda… - …, 1990 - Am Heart Assoc
We compared the efficacy and adverse effects of antihypertensive drug regimens in 690
men past age 60 with diastolic blood pressure 90-114 mm Hg and systolic blood pressure …

Effects of treatment for isolated systolic hypertension on cognitive status and depression in the elderly

BJ Gurland, J Teresi, WMF Smith… - Journal of the …, 1988 - Wiley Online Library
The Systolic Hypertension in the Elderly Program (SHEP) was designed as a feasibility
study and in part dealt with the effects of the treatment of isolated systolic hypertension on …

The effects of antihypertensive treatment on cognitive function: results from the HOPE study

JM Starr, LJ Whalley, IJ Deary - Journal of the American …, 1996 - Wiley Online Library
OBJECTIVES: Hypertension is associated with impaired cognition, but it is unclear whether
this impairment is reversible. We sought to evaluate the effect of blood pressure reduction on …

Treatment of hypertension in the elderly: III. Response of isolated systolic hypertension to various doses of hydrochlorothiazide: Results of a Department of Veterans …

WC Cushman, I Khatri, BJ Materson… - Archives of internal …, 1991 - jamanetwork.com
In a double-blind randomized study, we evaluated the effects of 25 mg vs 50 mg of
hydrochlorothiazide in 51 elderly patients (aged 68.9+-7.0 years) with isolated systolic …

Effect of hydrochlorothiazide, enalapril, and propranolol on quality of life and cognitive and motor function in hypertensive patients.

E McCorvey Jr, JT Wright Jr, JP Culbert… - Clinical …, 1993 - europepmc.org
The effect of hydrochlorothiazide, propranolol, and enalapril on cognitive and motor function
and quality of life (QOL) in hypertensive patients was studied. Patients> or= 55 years of age …

Impact of the treatment of isolated systolic hypertension on behavioral variables: results from the Systolic Hypertension in the Elderly Program

WB Applegate, S Pressel, J Wittes, J Luhr… - Archives of Internal …, 1994 - jamanetwork.com
Background: Little information has been published on the impact of antihypertensive
medications on quality of life in older persons. Particular concern has existed that lowering …

Health education program effects on the management of hypertension in the elderly

DE Morisky, DM Levine, LW Green… - Archives of Internal …, 1982 - jamanetwork.com
Because the elderly are viewed as having more difficulty in complying with therapy, this
analysis was directed at the effects of a health education program on their control of primary …

Antihypertensive therapy and quality of life: a comparison of atenolol, captopril, enalapril and propranolol.

SS Steiner, AJ Friedhoff, BL Wilson… - Journal of human …, 1990 - europepmc.org
This randomized, double-blind parallel study compared the effects of atenolol, captopril,
enalapril and propranolol in 360 men with mild-to-moderate essential hypertension. Patients …