Alterations in the structure of the airways, collectively termed airway remodelling, contribute
to airflow obstruction in a variety of chronic lung diseases. While histology has provided …

Airway remodelling is a well‐established feature in asthma and chronic obstructive lung
disease (COPD), secondary to chronic airway inflammation. The structural changes found …

Asthma and COPD are the most prevalent of lung diseases and contribute an enormous
burden of morbidity in North America and globally. In both conditions, inflammation leads to …

Airway remodeling is an established feature of asthma. Histologic examination is essential
in the assessment of remodeling that is a pathologic concept. Examinations of autopsied or …

Airway remodeling is extremely important in the pathophysiology of chronic obstructive
pulmonary disease (COPD). Since the site and nature of airflow obstruction was described …

Background: In some patients chronic asthma results in irreversible airflow obstruction. High
resolution computed tomography (HRCT) has been advocated for assessing the structural …

Ever since the site and nature of airflow obstruction in chronic obstructive pulmonary
disease was described by Hogg, Thurlbeck, and Macklem, investigators have been looking …

Chronic obstructive pulmonary disease (COPD) is described as airflow limitation that is not
fully reversible. Quantitative assessment of structural changes within the lung that are …

BACKGROUND: Few studies have directly compared airway remodelling assessed by
computed tomography (CT) between asthma and chronic obstructive pulmonary disease …

Background To prospectively apply an automated, quantitative three-dimensional approach
to imaging and airway analysis to assess airway remodeling in asthma patients. Methods …