The biology of glial cells and their complex roles in Alzheimer's disease: new opportunities in therapy
Even though Alzheimer's disease (AD) is of significant interest to the scientific community, its
pathogenesis is very complicated and not well-understood. A great deal of progress has …
pathogenesis is very complicated and not well-understood. A great deal of progress has …
Glial cells–The key elements of Alzheimer s disease
D Dzamba, L Harantova, O Butenko… - Current Alzheimer …, 2016 - ingentaconnect.com
Alzheimer's disease (AD) is a complex neurodegenerative disorder with major clinical
hallmarks of memory loss, dementia, and cognitive impairment. Besides the extensive …
hallmarks of memory loss, dementia, and cognitive impairment. Besides the extensive …
Key brain cell interactions and contributions to the pathogenesis of Alzheimer's disease
J Saavedra, M Nascimento, MA Liz… - Frontiers in Cell and …, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide, with
the two major hallmarks being the deposition of extracellular β-amyloid (Aβ) plaques and of …
the two major hallmarks being the deposition of extracellular β-amyloid (Aβ) plaques and of …
When astrocytes become harmful: functional and inflammatory responses that contribute to Alzheimer's disease
E Avila-Muñoz, C Arias - Ageing research reviews, 2014 - Elsevier
A growing body of research suggests that astrocytes play roles as contributors to the
pathophysiology of Alzheimer's disease (AD). Several lines of evidence propose that …
pathophysiology of Alzheimer's disease (AD). Several lines of evidence propose that …
[HTML][HTML] The Role of Glial Cells in Synaptic Dysfunction: Insights into Alzheimer's Disease Mechanisms
Y Yu, R Chen, K Mao, M Deng, Z Li - Aging and Disease, 2024 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a devastating neurodegenerative disorder that impacts a
substantial number of individuals globally. Despite its widespread prevalence, there is …
substantial number of individuals globally. Despite its widespread prevalence, there is …
Neuroprotective and neurotoxic properties of glial cells in the pathogenesis of Alzheimer's disease
D Farfara, V Lifshitz, D Frenkel - Journal of cellular and …, 2008 - Wiley Online Library
• Introduction• Innate immune response in the AD brain‐Microglia‐Astrocyte• Glial cells
mediate the peripheral immune response in AD‐Glial cell interaction with endothelial cells …
mediate the peripheral immune response in AD‐Glial cell interaction with endothelial cells …
Oligodendroglial cells in Alzheimer's disease
AM Butt, IC De La Rocha, A Rivera - Neuroglia in neurodegenerative …, 2019 - Springer
Oligodendrocytes form the myelin that ensheaths CNS axons, which is essential for rapid
neuronal signalling and underpins the massive computing power of the human brain …
neuronal signalling and underpins the massive computing power of the human brain …
[HTML][HTML] Astrocytes in Alzheimer's disease
The circuitry of the human brain is formed by neuronal networks embedded into astroglial
syncytia. The astrocytes perform numerous functions, providing for the overall brain …
syncytia. The astrocytes perform numerous functions, providing for the overall brain …
The contribution of astrocytes to Alzheimer's disease
AM Birch - Biochemical Society Transactions, 2014 - portlandpress.com
Astrocytes were historically classified as supporting cells; however, it is becoming
increasingly clear that they actively contribute to neuronal functioning under normal and …
increasingly clear that they actively contribute to neuronal functioning under normal and …
Glial cells in Alzheimer's disease: From neuropathological changes to therapeutic implications
MS Uddin, LW Lim - Ageing research reviews, 2022 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that usually develops slowly and
progressively worsens over time. Although there has been increasing research interest in …
progressively worsens over time. Although there has been increasing research interest in …