Evidence from both human and animal studies has shown that the prenatal and early
postnatal environments influence susceptibility to chronic disease in later life and suggests …

Abstract Changes in epigenetic marks such as DNA methylation and histone acetylation are
associated with a broad range of disease traits, including cancer, asthma, metabolic …

Epigenetics, and especially DNA methylation, have recently become provocative biological
explanations for early-life environmental effects on later health. Despite the large increase in …

Literature on maternal exposures and the risk of epigenetic changes or diseases in the
offspring is growing. Paternal contributions are often not considered. However, some animal …

Environmental exposures, psychosocial stressors and nutrition are all potentially important
influences that may impact health outcomes directly or via interactions with the genome or …

The epigenome consists of the DNA methylation marks and histone modifications involved
in controlling gene expression. It is accurately reproduced during mitosis and can be …

Environmental epigenetics describes how environmental factors affect cellular epigenetics
and, hence, human health. Epigenetic marks alter the spatial conformation of chromatin to …

Epigenetic phenomena in animals and plants are mediated by DNA methylation and stable
chromatin modifications. There has been considerable interest in whether environmental …

Environmental epigenetics has an important role in regulating phenotype formation or
disease etiology. The ability of environmental factors and exposures early in life to alter …

Environmental insults, such as exposure to toxicants or nutritional abnormalities, can lead to
epigenetic changes that are in turn related to increased susceptibility to disease. The focus …