The earliest indications for paternally induced transgenerational effects from the
environment to future generations were based on a small number of long-term …

Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …

World-wide, research initiatives are in progress to establish the role of the epigenome in
human disease. Empirical data are still scarce, but particularly studies investigating how the …

The ability of environmental factors to promote a phenotype or disease state not only in the
individual exposed but also in subsequent progeny for successive generations is termed …

Epigenetics has the potential to explain various biological phenomena that have heretofore
defied complete explication. This review describes the various types of endogenous human …

Environmental toxicants can alter epigenetic regulatory features such as DNA methylation
and microRNA expression. As the sensitivity of epigenomic regulatory features may be …

Environmental influence on developmental plasticity impacts a wide diversity of animal life
from insects to humans. We now understand the epigenetic basis for many of these altered …

Objective Health or disease is shaped for all individuals by interactions between their genes
and environment. Exactly how the environment changes gene expression and how this can …

The ability of an environmental factor or toxicant to promote a phenotype or disease state not
only in the individual exposed, but also in subsequent progeny for multiple generations, is …

This review focuses on how environmental factors through epigenetics modify disease risk
and health outcomes. Major epigenetic events, such as histone modifications, DNA …