Effects of n-3 PUFA enriched and n-3 PUFA deficient diets in naïve and Aβ-treated female rats

M Bove, E Mhillaj, P Tucci, I Giardino… - Biochemical …, 2018 - Elsevier
Depression is one of the most common psychiatric diseases and the prevalence of
depressive symptoms in women is almost twice compared to men, although the reasons of …

N-3 PUFA diet enrichment prevents amyloid beta-induced depressive-like phenotype

MG Morgese, S Schiavone, E Mhillaj, M Bove… - Pharmacological …, 2018 - Elsevier
Among neuropsychiatric diseases, depression is one of the most prevalent. Many
pathologies have been indicated as comorbid with depression and in particular …

N-3 PUFA improved post-menopausal depression induced by maternal separation and chronic mild stress through serotonergic pathway in rats—effect associated …

JE Choi, K Borkowski, JW Newman, Y Park - The Journal of Nutritional …, 2021 - Elsevier
Early life maternal separation (MS) increases the vulnerability to depression in rats with
chronic mild stress (CMS). N-3 polyunsaturated fatty acids (PUFA) improved depressive …

N-3 PUFA prevent oxidative stress in a rat model of beta-amyloid-induced toxicity

MG Morgese, S Schiavone, M Bove, AL Colia… - Pharmaceuticals, 2021 - mdpi.com
Polyunsaturated fatty acids (PUFA) are involved in brain disorders associated to amyloid
beta (Aβ) toxicity for which oxidative stress, neurochemical dysfunctions, and …

N-3 PUFA have antidepressant-like effects via improvement of the HPA-axis and neurotransmission in rats exposed to combined stress

EY Kim, JE Choi, M Kim, J Hong, Y Park - Molecular Neurobiology, 2020 - Springer
Early life and adulthood stress increase vulnerability for mental illness, and eventually
trigger depression. N-3 polyunsaturated fatty acids (PUFA) have antidepressant effects, but …

Dietary n-3 PUFAs deficiency increases vulnerability to inflammation-induced spatial memory impairment

JC Delpech, A Thomazeau, C Madore… - …, 2015 - nature.com
Dietary n-3 polyunsaturated fatty acids (PUFAs) are critical components of inflammatory
response and memory impairment. However, the mechanisms underlying the sensitizing …

n-3 Polyunsaturated fatty acid supplementation restored impaired memory and GABAergic synaptic efficacy in the hippocampus of stressed rats

MÁ Pérez, V Peñaloza-Sancho, J Ahumada… - Nutritional …, 2018 - Taylor & Francis
While chronic stress induces dendritic atrophy in the hippocampus and impairs learning and
memory, supplementation with n-3 polyunsaturated fatty acids (n-3 PUFA) is known to …

PUFA induce antidepressant-like effects in parallel to structural and molecular changes in the hippocampus

VR Venna, D Deplanque, C Allet, K Belarbi… - …, 2009 - Elsevier
Epidemiological data suggest that omega-3 polyunsaturated fatty acids (PUFA) consumption
may be inversely correlated to the prevalence and severity of depression but little is known …

Depressive-like phenotype evoked by lifelong nutritional omega-3 deficiency in female rats: Crosstalk among kynurenine, Toll-like receptors and amyloid beta …

MG Morgese, S Schiavone, AB Maffione, P Tucci… - Brain, Behavior, and …, 2020 - Elsevier
Depression is one of the most common psychiatric diseases and the prevalence of
depressive symptoms in women is almost twice compared to men, although the reasons of …

[HTML][HTML] n-3 polyunsaturated fatty acids supplementation enhances hippocampal functionality in aged mice

D Cutuli, P De Bartolo, P Caporali… - Frontiers in aging …, 2014 - frontiersin.org
As major components of neuronal membranes, omega-3 polyunsaturated acids (n-3 PUFA)
exhibit a wide range of regulatory functions, modulating from synaptic plasticity to …