The production of proteins in appropriate quantity and quality is an essential requirement of
the present time. There appears to be a progressive increase in the application of …

The expression of cloned genes in mammalian cells is a basic tool for understanding gene
expression, protein structure, and function, and biological regulatory mechanisms. The level …

The demand for recombinant therapeutic proteins is significantly increasing. There is a
constant need to improve the existing expression systems, and also developing novel …

From 2006 to 2011, an average of 15 novel recombinant protein therapeutics have been
approved by US Food and Drug Administration (FDA) annually. In addition, the expiration of …

The proteins produced in the body control and mediate the metabolic processes and help in
its routine functioning. Any kind of impairment in protein production, such as production of …

Cell‐free protein synthesis has emerged as a powerful technology for rapid and efficient
protein production. Cell‐free methods are also amenable to automation and such systems …

Before utilization in biomedical diagnosis, therapeutic treatment, and biotechnology, the
diverse variety of peptides and proteins must be preliminarily purified and thoroughly …

Different systems are being studied and used to prepare recombinant proteins for
pharmaceutical use. The blood, and still more the milk, from transgenic animals appear a …

Bacteria have long been the favorite expression system for recombinant protein production.
However, the flaw of the system is that insoluble and inactive proteins are co-produced due …

Gene therapy aims at transferring a therapeutic gene into human somatic cells in order to
treat a disease. Originally addressed to hereditary genetic disorders, gene therapy has …