Klebsiella pneumoniae isolates that produce carbapenemases (KPCs) are rapidly
disseminating worldwide. To determine their genetic background, we investigated 16 bla …

Objectives Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella
pneumoniae has spread rapidly in China. In this study, we aimed to investigate the …

Klebsiella pneumoniae carbapenemase (KPC) variants, which refer to the substitution,
insertion, or deletion of amino acid sequence compared to wild bla KPC type, have reduced …

Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae have
emerged as major nosocomial pathogens. bla KPC, commonly located on Tn 4401, is found …

The extended-spectrum-β-lactamase (ESBL)-and Klebsiella pneumoniae carbapenemase
(KPC)-producing Enterobacteriaceae represent serious and urgent threats to public health …

Carbapenem resistance mediated by plasmid-borne Klebsiella pneumoniae
carbapenemases (KPC) is an emerging problem of significant clinical importance in Gram …

Background KPC carbapenemase-producing Klebsiella pneumoniae isolates have been
increasingly detected in Europe. We report the first KPC-producing isolates characterized in …

Background The emergence of bla KPC-containing Klebsiella pneumoniae (KPC-Kp)
isolates is attracting significant attention. Outbreaks in the Eastern USA have created serious …

Background The class A carbapenemase KPC has disseminated rapidly worldwide,
challenging the treatment of Gram-negative infections. This report describes the first KPC …

The convergence of carbapenem-resistance and hypervirulence genes in Klebsiella
pneumoniae has led to the emergence of highly drug-resistant superbugs capable of …