AQP4 antibodies in neuromyelitis optica: diagnostic and pathogenetic relevance
S Jarius, B Wildemann - Nature Reviews Neurology, 2010 - nature.com
Antibodies to aquaporin-4 (also known as AQP4-Ab or NMO-IgG) are sensitive and highly
specific serum markers of autoimmune neuromyelitis optica (NMO). Second-generation …
specific serum markers of autoimmune neuromyelitis optica (NMO). Second-generation …
Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance
Abstract Background In 70-80% of cases, neuromyelitis optica (NMO) is associated with
highly specific serum auto-antibodies to aquaporin-4 (termed AQP4-Ab or NMO-IgG) …
highly specific serum auto-antibodies to aquaporin-4 (termed AQP4-Ab or NMO-IgG) …
Antibody to aquaporin-4 in the long-term course of neuromyelitis optica
S Jarius, F Aboul-Enein, P Waters, B Kuenz, A Hauser… - Brain, 2008 - academic.oup.com
Neuromyelitis optica (NMO) is a severe inflammatory CNS disorder of putative autoimmune
aetiology, which predominantly affects the spinal cord and optic nerves. Recently, a highly …
aetiology, which predominantly affects the spinal cord and optic nerves. Recently, a highly …
Neuromyelitis optica pathogenesis and aquaporin 4
DJ Graber, M Levy, D Kerr, WF Wade - Journal of neuroinflammation, 2008 - Springer
Neuromyelitis optica (NMO) is a severe, debilitating human disease that predominantly
features immunopathology in the optic nerves and the spinal cord. An IgG1 autoantibody …
features immunopathology in the optic nerves and the spinal cord. An IgG1 autoantibody …
Aquaporin-4 autoimmunity
A Zekeridou, VA Lennon - Neuroimmunology & Neuroinflammation, 2015 - AAN Enterprises
Neuromyelitis optica (NMO) and a related spectrum of inflammatory CNS disorders are
unified by detection of a serum autoantibody specific for the aquaporin-4 (AQP4) water …
unified by detection of a serum autoantibody specific for the aquaporin-4 (AQP4) water …
Antibody to aquaporin 4 in the diagnosis of neuromyelitis optica
Background Neuromyelitis optica (NMO) is a demyelinating disease of the central nervous
system (CNS) of putative autoimmune aetiology. Early discrimination between multiple …
system (CNS) of putative autoimmune aetiology. Early discrimination between multiple …
Mechanisms of disease: aquaporin-4 antibodies in neuromyelitis optica
Neuromyelitis optica (NMO) is a rare CNS inflammatory disorder that predominantly affects
the optic nerves and spinal cord. Recent serological findings strongly suggest that NMO is a …
the optic nerves and spinal cord. Recent serological findings strongly suggest that NMO is a …
Evaluation of aquaporin‐4 antibody assays
PJ Waters, SJ Pittock, JL Bennett… - Clinical and …, 2014 - Wiley Online Library
Abstract Aquaporin‐4 (AQP 4) is a water channel protein that is most highly, but not
exclusively, expressed in the central nervous system. In 2005 AQP 4 was shown to be the …
exclusively, expressed in the central nervous system. In 2005 AQP 4 was shown to be the …
Aquaporin-4 antibody–negative neuromyelitis optica: distinct assay sensitivity–dependent entity
R Marignier, R Bernard-Valnet, P Giraudon… - Neurology, 2013 - AAN Enterprises
Objective: To optimize aquaporin-4 (AQP4) antibody (Ab) detection and to assess the
influence of the increased sensitivity of the assay on the demographic and disease-related …
influence of the increased sensitivity of the assay on the demographic and disease-related …
Aquaporin‐4 antibodies (NMO‐IgG) as a serological marker of neuromyelitis optica: a critical review of the literature
S Jarius, B Wildemann - Brain pathology, 2013 - Wiley Online Library
Antibodies to aquaporin‐4 (called NMO‐IgG or AQP4‐Ab) constitute a sensitive and highly
specific serum marker of neuromyelitis optica (NMO) that can facilitate the differential …
specific serum marker of neuromyelitis optica (NMO) that can facilitate the differential …