[HTML][HTML] Effective connectivity of the right anterior insula in schizophrenia: the salience network and task-negative to task-positive transition

Q Luo, B Pan, H Gu, M Simmonite, S Francis… - NeuroImage: Clinical, 2020 - Elsevier
Triple network dysfunction theory of schizophrenia postulates that the interaction between
the default-mode and the fronto-parietal executive network is disrupted by aberrant salience …

Disruption of anterior insula modulation of large-scale brain networks in schizophrenia

LV Moran, MA Tagamets, H Sampath, A O'Donnell… - Biological …, 2013 - Elsevier
Background Systems level modeling of functional magnetic resonance imaging data has
demonstrated dysfunction of several large-scale brain networks in schizophrenia. Anomalies …

Aberrant dependence of default mode/central executive network interactions on anterior insular salience network activity in schizophrenia

A Manoliu, V Riedl, A Zherdin, M Mühlau… - Schizophrenia …, 2014 - academic.oup.com
In schizophrenia, consistent structural and functional changes have been demonstrated for
the insula including aberrant salience processing, which is critical for psychosis. Interactions …

Structural connectivity of the salience-executive loop in schizophrenia

SJ Iwabuchi, PF Liddle, L Palaniyappan - European archives of psychiatry …, 2015 - Springer
Previously, differences have been shown in effective connectivity of the salience network
between healthy controls and patients with schizophrenia. Specifically, the right anterior …

[HTML][HTML] Trait related aberrant connectivity in clinically stable patients with schizophrenia: A seed based resting state fMRI study

PA Lalousis, A Malaviya, R Upthegrove… - Brain imaging and …, 2022 - Springer
Aberrant resting-state connectivity within and between the Default Mode Network, the
Executive Control Network, and the Salience Network is well-established in schizophrenia …

Does the salience network play a cardinal role in psychosis? An emerging hypothesis of insular dysfunction

L Palaniyappan, PF Liddle - Journal of Psychiatry and Neuroscience, 2012 - jpn.ca
The insular cortex is one of the brain regions that show consistent abnormalities in both
structural and functional neuroimaging studies of schizophrenia. In healthy individuals, the …

[HTML][HTML] Patients with schizophrenia fail to up-regulate task-positive and down-regulate task-negative brain networks: an fMRI study using an ICA analysis approach

M Nygård, T Eichele, EM Løberg… - Frontiers in Human …, 2012 - frontiersin.org
Recent research suggests that the cerebral correlates of cognitive deficits in schizophrenia
are nested in the activity of widespread, inter-regional networks rather than being restricted …

Salience network-midbrain dysconnectivity and blunted reward signals in schizophrenia

VB Gradin, G Waiter, A O'Connor, L Romaniuk… - Psychiatry Research …, 2013 - Elsevier
Theories of schizophrenia propose that abnormal functioning of the neural reward system is
linked to negative and psychotic symptoms, by disruption of reward processing and …

[HTML][HTML] Aberrant functional connectivity in the default mode and central executive networks in subjects with schizophrenia–a whole-brain resting-state ICA study

H Littow, V Huossa, S Karjalainen… - Frontiers in …, 2015 - frontiersin.org
Neurophysiological changes of schizophrenia are currently linked to disturbances in
connectivity between functional brain networks. Functional magnetic resonance imaging …

[HTML][HTML] Insular dysfunction reflects altered between-network connectivity and severity of negative symptoms in schizophrenia during psychotic remission

A Manoliu, V Riedl, A Doll, JG Bäuml… - Frontiers in human …, 2013 - frontiersin.org
Schizophrenia is characterized by aberrant intrinsic functional connectivity (iFC) within and
between intrinsic connectivity networks (ICNs), including the Default Mode-(DMN), Salience …