Meat mutagens and breast cancer in postmenopausal women—a cohort analysis

K Wu, R Sinha, MD Holmes, E Giovannucci… - … , biomarkers & prevention, 2010 - AACR
Background: Mutagenic compounds produced when meats are cooked at high temperatures
have been hypothesized to increase risk of breast cancer. Methods: We examined the …

Well-done meat intake and meat-derived mutagen exposures in relation to breast cancer risk: the Nashville Breast Health Study

Z Fu, SL Deming, AM Fair, MJ Shrubsole… - Breast cancer research …, 2011 - Springer
Previous studies of the association of meat intake and meat-derived mutagen exposure with
breast cancer risk have produced inconsistent results. We evaluated this association in a …

Meat intake and meat preparation in relation to risk of postmenopausal breast cancer in the NIH‐AARP diet and health study

GC Kabat, AJ Cross, Y Park, A Schatzkin… - … journal of cancer, 2009 - Wiley Online Library
A number of studies have reported that intake of red meat or meat cooked at high
temperatures is associated with increased risk of breast cancer, but other studies have …

Well-done meat intake and the risk of breast cancer

W Zheng, DR Gustafson, D Moore… - Journal of the …, 1998 - academic.oup.com
Background: Heterocyclic amines, mutagens formed in meats cooked at high temperatures,
have been demonstrated as mammary carcinogens in animals. We conducted a nested …

Association between meat consumption and risk of breast cancer: Findings from the Sister Study

JJ Lo, YMM Park, R Sinha… - International journal of …, 2020 - Wiley Online Library
Meat consumption has been postulated to increase the risk of breast cancer, but this
association has not been consistently seen. We examined the association between …

Cooked meat and risk of breast cancer—lifetime versus recent dietary intake

SE Steck, MM Gaudet, SM Eng, JA Britton… - …, 2007 - journals.lww.com
Background: Polycyclic aromatic hydrocarbons (PAHs) and heterocyclic amines (HCAs) are
carcinogens formed in or on the surface of well-done meat, cooked at high temperature …

An epidemiologic approach to studying heterocyclic amines

R Sinha - … Research/Fundamental and Molecular Mechanisms of …, 2002 - Elsevier
Diets containing substantial amounts of red meat may increase the risk of colorectal,
pancreatic, breast, prostate, and renal cancer. The association with red meat intake may be …

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, a Carcinogen in High- Temperature-Cooked Meat, and Breast Cancer Risk

R Sinha, DR Gustafson, M Kulldorff… - Journal of the …, 2000 - academic.oup.com
Although intake of well-done red meat has been associated with an increased risk of breast
cancer (1), it is unclear what component (s) of well-done red meat is associated with this risk …

Human exposure to heterocyclic amine food mutagens/carcinogens: relevance to breast cancer

JS Felton, MG Knize, CP Salmon… - Environmental and …, 2002 - Wiley Online Library
Heterocyclic amines produced from overcooked foods are extremely mutagenic in numerous
in vitro and in vivo test systems. One of these mutagens, 2‐amino‐1‐methyl‐6 …

A prospective analysis of meat mutagens and colorectal cancer in the Nurses' Health Study and Health Professionals Follow-up Study

NT Le, FAS Michels, M Song, X Zhang… - Environmental …, 2016 - ehp.niehs.nih.gov
Background: Heterocyclic amines (HCAs) in cooked meats may play a role in colorectal
cancer (CRC) development. Objectives: We aimed to prospectively examine the association …