Role of Kidney Derived Extracellular Vesicles Containing Mitochondrial Proteins and Splicing Factors in Renal Fibrosis: FR-PO981

KP Maremanda, CR Chowdhury, AK Ajay… - Journal of the …, 2022 - journals.lww.com
Background: Extracellular vesicles (EVs) are lipid bilayer nanoparticles enriched with
biomolecules such as DNAs, RNAs, protein and lipids. They help in cellular communication …

Research progress of extracellular vesicles in the treatment of renal disease

TT Tang, LL Lyu, BC Liu - Sheng li xue bao:[Acta Physiologica …, 2022 - europepmc.org
Extracellular vesicles (EVs) are lipid bilayer-enclosed structures containing diverse bioactive
cargoes that play a major role in intercellular communication in both physiological and …

Extracellular vesicles and acute kidney injury: potential therapeutic avenue for renal repair and regeneration

M Kosanović, B Milutinovic, S Glamočlija… - International journal of …, 2022 - mdpi.com
Acute kidney injury (AKI) is a sudden decline of renal function and represents a global
clinical problem due to an elevated morbidity and mortality. Despite many efforts, currently …

Extracellular vesicles in renal disease

D Karpman, A Ståhl, I Arvidsson - Nature Reviews Nephrology, 2017 - nature.com
Extracellular vesicles, such as exosomes and microvesicles, are host cell-derived packages
of information that allow cell–cell communication and enable cells to rid themselves of …

Fibrosis: etiology, pathophysiology, measurements, and therapy

Y Liu, J Xu, Y Zhao, P Hao - Frontiers in Pharmacology, 2023 - frontiersin.org
Various stress injuries can cause organ fibrosis, depending on different pathogeneses and
mechanisms. Excessive fibrosis aggravates pathological remodeling and functional …

Extracellular vesicles as source of biomarkers in glomerulonephritis

M Bruschi, G Candiano, A Angeletti, F Lugani… - International journal of …, 2023 - mdpi.com
Kidney disease is a global health and healthcare burden. Glomerulonephritis (Gn), both
primary and secondary, is generally characterized by an inflammatory glomerular injury and …

Exploring the role of urinary extracellular vesicles in kidney physiology, aging, and disease progression

C Grange, A Dalmasso, JJ Cortez… - … of Physiology-Cell …, 2023 - journals.physiology.org
Extracellular vesicles (EVs), membranous vesicles present in all body fluids, are considered
important messengers, carrying their information over long distance and modulating the …

Extracellular vesicles: emerging roles, biomarkers and therapeutic strategies in fibrotic diseases

J Zhu, S Wang, D Yang, W Xu, H Qian - Journal of Nanobiotechnology, 2023 - Springer
Extracellular vesicles (EVs), a cluster of cell-secreted lipid bilayer nanoscale particles,
universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past …

The nephroprotective properties of extracellular vesicles in experimental models of chronic kidney disease: A systematic review

N Nowak, M Yamanouchi, E Satake - Stem cell reviews and reports, 2022 - Springer
Extracellular vesicle (EV)-based therapy was hypothesized as a promising regenerative
approach which has led to intensive research of EVs in various pathologies. In this study, we …

Extracellular vesicles in redox signaling and metabolic regulation in chronic kidney disease

OE Aparicio-Trejo, AK Aranda-Rivera, H Osorio-Alonso… - Antioxidants, 2022 - mdpi.com
Chronic kidney disease (CKD) is a world health problem increasing dramatically. The onset
of CKD is driven by several mechanisms; among them, metabolic reprogramming and …