[HTML][HTML] Extracellular vesicles in kidney development and pediatric kidney diseases

T Ergunay, F Collino, G Bianchi, S Sedrakyan… - Pediatric …, 2023 - Springer
Extracellular vesicles (EVs) are membranous cargo particles that mediate intercellular
communication. They are heterogeneous in size and mechanism of release, and found in all …

Extracellular vesicles in renal diseases: more than novel biomarkers?

U Erdbrügger, TH Le - Journal of the American Society of …, 2016 - journals.lww.com
Extracellular vesicles from the urine and circulation have gained significant interest as
potential diagnostic biomarkers in renal diseases. Urinary extracellular vesicles contain …

[HTML][HTML] Extracellular vesicles as regulators of kidney function and disease

F Behrens, J Holle, WM Kuebler, S Simmons - Intensive care medicine …, 2020 - Springer
Extracellular vesicles (EVs) are small, lipid bilayer-delimited particles of cellular origin that
recently gained increasing attention for their potential use as diagnostic biomarkers, and …

Extracellular vesicles mediate cellular interactions in renal diseases—novel views of intercellular communications in the kidney

PL Zhang, ML Liu - Journal of cellular physiology, 2021 - Wiley Online Library
The kidney is a complicated and important internal organ receiving approximately 20% of
the cardiac output and mediates numerous pathophysiologic actions. These include …

[HTML][HTML] Urinary extracellular vesicles as biomarkers of kidney disease: from diagnostics to therapeutics

IO Sun, LO Lerman - Diagnostics, 2020 - mdpi.com
Cell-derived extracellular vesicles (EVs) can be isolated from various body fluids, including
urine. Urinary EVs have gained important recognition as potential diagnostic biomarkers in …

Urinary extracellular vesicles and the kidney: biomarkers and beyond

M Salih, R Zietse, EJ Hoorn - American Journal of …, 2014 - journals.physiology.org
Extracellular vesicles have been isolated in various body fluids, including urine. The cargo
of urinary extracellular vesicles (uEVs) is composed of proteins and nucleic acids reflecting …

Mesenchymal stem cell‐derived extracellular vesicles in treatment against renal fibrosis

J Wang, J Cui, S Yu, S Xia - Clinical and Translational …, 2023 - Wiley Online Library
Background Renal fibrosis (RF) is the main pathological pathway of acute kidney injury and
chronic kidney disease. Its main pathological feature is extracellular matrix aggregation in …

[HTML][HTML] Potential therapeutic effect and mechanisms of mesenchymal stem cells-extracellular vesicles in renal fibrosis

C Liao, G Chen, Q Yang, Y Liu, T Zhou - Frontiers in Cell and …, 2022 - frontiersin.org
Renal fibrosis (RF) is central pathological pathway for kidney diseases, with the main
pathological features being the aberrant accumulation of myofibroblasts that produce …

[HTML][HTML] Exosomes from tubular epithelial cells undergoing epithelial‐to‐mesenchymal transition promote renal fibrosis by M1 macrophage activation

Y Lu, R Zhang, X Gu, X Wang, P Xi, X Chen - FASEB BioAdvances, 2023 - ncbi.nlm.nih.gov
Kidney fibrosis is the common final pathway of chronic kidney disease (CKD), and it is
distinguished by inflammation, mesenchymal transition with myofibroblast formation, and …

[HTML][HTML] The Roles of Extracellular Vesicles in the Progression of Renal Cell Carcinoma and Their Potential for Future Clinical Application

M Takeda, S Akamatsu, Y Kita, T Goto, T Kobayashi - Nanomaterials, 2023 - mdpi.com
Renal cell carcinoma (RCC) is the most common type of kidney cancer and is thought to
originate from renal tubular epithelial cells. Extracellular vesicles (EVs) are nanosized lipid …