Biogenesis, membrane trafficking, functions, and next generation nanotherapeutics medicine of extracellular vesicles

S Gurunathan, MH Kang, M Qasim… - International Journal of …, 2021 - Taylor & Francis
Extracellular vesicles (EVs) are a heterogeneous group of membrane-limited vesicles and
multi-signal messengers loaded with biomolecules. Exosomes and ectosomes are two …

[HTML][HTML] Naïve or engineered extracellular vesicles from different cell sources: therapeutic tools for kidney diseases

E Ceccotti, G Saccu, MB Herrera Sanchez, S Bruno - Pharmaceutics, 2023 - mdpi.com
Renal pathophysiology is a multifactorial process involving different kidney structures. Acute
kidney injury (AKI) is a clinical condition characterized by tubular necrosis and glomerular …

Regulation of regulated cell death by extracellular vesicles in acute kidney injury and chronic kidney disease

Z Zhou, L Shi, B Chen, H Qian - Cytokine & Growth Factor Reviews, 2023 - Elsevier
The imbalance between proliferation and death of kidney resident cells is a crucial factor in
the development of acute or chronic renal dysfunction. Acute kidney injury (AKI) is often …

Research progress on the role of extracellular vesicles in the pathogenesis of diabetic kidney disease

J Jin, M Zhang - Renal Failure, 2024 - Taylor & Francis
Diabetic kidney disease (DKD) is a serious complication of diabetes mellitus (DM) and has
become the main cause of end-stage renal disease worldwide. In recent years, with the …

[HTML][HTML] Extracellular vesicles in organ fibrosis: mechanisms, therapies, and diagnostics

DR Brigstock - Cells, 2021 - mdpi.com
Fibrosis is the unrelenting deposition of excessively large amounts of insoluble interstitial
collagen due to profound matrigenic activities of wound-associated myofibroblasts during …

Stem cell-derived extracellular vesicles for renal repair: do cardiovascular comorbidities matter?

A Eirin, LO Lerman - American Journal of Physiology-Renal …, 2019 - journals.physiology.org
Extracellular vesicle (EV)-based regenerative therapy has shown promising results in
preclinical models of renal disease and might be useful for patients with several forms of …

Urinary extracellular vesicles: Origin, role as intercellular messengers and biomarkers; efficient sorting and potential treatment options

P Svenningsen, R Sabaratnam, BL Jensen - Acta Physiologica, 2020 - Wiley Online Library
Urinary extracellular vesicles (uEVs) are a heterogenous group of vesicles consisting mainly
of microvesicles and exosomes that originate predominantly (99.96%) from kidney, the …

[HTML][HTML] Extracellular vesicles in renal physiology and clinical applications for renal disease

SH Kwon - The Korean journal of internal medicine, 2019 - ncbi.nlm.nih.gov
Many cells in the nephron release extracellular vesicles (EVs). EVs envelop nucleic acids,
proteins, and lipids. The surfaces of EVs express donor cell-specific markers, ligands, and …

[HTML][HTML] Extracellular vesicles tune the immune system in renal disease: a focus on systemic lupus erythematosus, antiphospholipid syndrome, thrombotic …

M Mazzariol, G Camussi, MF Brizzi - International journal of molecular …, 2021 - mdpi.com
Extracellular vesicles (EV) are microparticles released in biological fluids by different cell
types, both in physiological and pathological conditions. Owing to their ability to carry and …

[图书][B] Extracellular Vesicles: Applications and Therapeutic Potential

M Paul, T Brzozowski - 2024 - books.google.com
This edited volume, Extracellular Vesicles-Applications and Therapeutic Potential, provides
a comprehensive overview of the emerging data confirming the involvement of extracellular …