Current evidence indicates that regulatory T cells (Tregs) actively suppress autoreactive
lymphocytes that escape central tolerance. 1 2 Tregs are characterised by a high intensity …

Objectives: To characterise and quantify the CD4+ CD25+ T cell population in patients with
systemic lupus erythematosus (SLE) and to detect the possible influence of treatments and …

Regulatory T (Treg) cells play an important role in controlling immune responses. Their
frequency is decreased in many autoimmune diseases, including rheumatoid arthritis (RA) …

Regulatory T cells (Tregs) are supposed to stop immune responses in the course of immune
activation. However, chronic activation of immune system in systemic lupus erythematosus …

Regulatory T cells have an important role in the control of self-reactivity, and in the
pathogenesis of autoimmune inflammatory conditions. The aim of this work was to perform a …

Objective To explore whether there are extrinsic factors that impair the suppressive function
of CD4+, CD25+ regulatory T cells in patients with untreated active systemic lupus …

Objectives: Regulatory T cells (Tregs) are inversely correlated to disease activity in systemic
lupus erythematosus (SLE). However, little is known concerning the influence of …

The objective of the study was that the regulatory T cells (Treg) that specialize in the
suppression of immune responses might be critically involved in the pathogenesis of …

Objective: The identification of regulatory T cells (Treg cells) as CD4+ CD25high cells may
be upset by the increased frequency of activated effector T cells (Teff cells) in inflammatory …

Background: Circulating regulatory T cells (Tregs) are responsible for mediating immune
tolerance and maintaining immunological homeostasis. Decreases in Tregs may be …