Background During pulsed field ablation (PFA), electrode-tissue proximity optimizes lesion
quality. A novel “single-shot” map-and-ablate spherical multielectrode PFA array catheter …

Methods The spherical PFA catheter (Globe G4; Kardium Inc.) is delivered by a deflectable
16Fr transeptal sheath, under general anesthesia and ICE-guidance. The custom mapping …

Background Despite the promise of pulsed field ablation (PFA), there is much about the
biophysics of this novel energy technology that remains to be understood. Preclinical studies …

Background Preclinical studies with pulsed field ablation (PFA) revealed that electrode-
tissue proximity increases the likelihood of transmural lesions by maximizing electric field …

Background Pulsed‐field ablation (PFA) yields a novel ablation technology for atrial
fibrillation (AF). PFA lesions promise to be highly durable, however clinical data on lesion …

Background Preclinical studies have revealed that pulsed field ablation (PFA) lesion
dimensions increase with repetitive applications at a similar electric field. Objectives This …

Background Pulsed field ablation (PFA) yields a novel ablation technology for atrial
fibrillation (AF). PFA lesions promise to be highly durable, however clinical data on lesion …

Background Because of its safety,“single-shot” pulsed field ablation (PFA) catheters have
been developed for pulmonary vein isolation (PVI). However, most atrial fibrillation (AF) …

Background Data from clinical trials of pulsed field ablation (PFA) to treat atrial fibrillation
(AF) indicate highly-efficient workflow, an excellent safety profile, good clinical outcomes …

Catheter ablation is the cornerstone treatment of atrial arrhythmias by restoring sinus rhythm,
reducing symptoms, and improving quality of life. 1, 2 Thermal energy sources, including …