A minipig model of high-fat/high-sucrose diet-induced diabetes and atherosclerosis.

XSM Xi ShouMin, YWD Yin WeiDong… - 2004 - cabidigitallibrary.org
Type 2 diabetes is a major risk factor of the development of atherosclerosis in humans.
However, studies examining mechanisms underlying diabetes-accelerated atherosclerosis …

A minipig model of high‐fat/high‐sucrose diet‐induced diabetes and atherosclerosis

S Xi, W Yin, Z Wang, M Kusunoki, X Lian… - International journal …, 2004 - Wiley Online Library
Type 2 diabetes is a major risk factor of the development of atherosclerosis in humans.
However, studies examining mechanisms underlying diabetes‐accelerated atherosclerosis …

Dyslipidemia and vascular dysfunction in diabetic pigs fed an atherogenic diet

JL Dixon, JD Stoops, JL Parker… - … , and vascular biology, 1999 - Am Heart Assoc
Diabetic patients typically have not only hyperglycemia but also dyslipidemia. Study of the
pathogenic components of the diabetic milieu and mechanisms of accelerated …

Complex porcine model of atherosclerosis: induction of early coronary lesions after long-term hyperlipidemia without sustained hyperglycemia

S Artinger, C Deiner, C Loddenkemper… - Canadian Journal of …, 2009 - Elsevier
Background The incidence of coronary artery disease (CAD) is still increasing in
industrialized countries and it is even higher in diabetic patients. For experimental studies …

Diabetes-induced accelerated atherosclerosis in swine

RG Gerrity, R Natarajan, JL Nadler, T Kimsey - Diabetes, 2001 - Am Diabetes Assoc
Patients with diabetes are at higher risk for atherosclerotic disease than nondiabetic
individuals with other comparable risk factors. Studies examining mechanisms underlying …

C57BL/6 mice fed high fat diets as models for diabetes-accelerated atherosclerosis

SA Schreyer, DL Wilson, RC LeBoeuf - Atherosclerosis, 1998 - Elsevier
Non-insulin-dependent diabetes mellitus (NIDDM) is a major risk factor for the development
of atherosclerosis in humans. The development of an animal model that displays …

Establishment of Type 2 Diabetes Mellitus Models Using High-Fat Diet and STZ in Bama Minipigs

Y Zhao, M Niu, J Yunxiao, Y Jifang, X Lei, D Xin… - 2021 - researchsquare.com
Background In the past 20 years, the number of adults with diabetes has tripled. For most of
the researches are often conducted in rodent T2DM models, and effective drugs developed …

[PDF][PDF] Swine as a model of experimental atherosclerosis

R Pasławski, U Pasławska, J Nicpoń… - Adv Clin Exp …, 2011 - advances.umw.edu.pl
In Western countries, lifestyle changes in the past century are considered to be a major
factor in obesity and related diseases such as atherosclerosis and diabetes. To gain a better …

Rapid development of atherosclerosis in the world's smallest microminipig fed a high-fat/high-cholesterol diet a useful animal model due to its size and similarity to …

K Hiroaki, Y Tomonobu, M Naoki, A Makoto… - … of Atherosclerosis and …, 2014 - cir.nii.ac.jp
Aim: Experimental studies of human atherogenesis require an appropriate animal model
that mimics human physiology and pathology. Because swine physiology is similar to …

Rapid development of atherosclerosis in the world's smallest microminipig fed a high-fat/high-cholesterol diet a useful animal model due to its size and similarity to …

H Kawaguchi, T Yamada, N Miura, M Ayaori… - … of Atherosclerosis and …, 2014 - jstage.jst.go.jp
Aim: Experimental studies of human atherogenesis require an appropriate animal model
that mimics human physiology and pathology. Because swine physiology is similar to …