Converting-enzyme inhibitor enalapril (MK421) in treatment of hypertension with renal artery stenosis.

GP Hodsman, JJ Brown, DL Davies, R Fraser… - Br Med J (Clin Res …, 1982 - bmj.com
Enalapril maleate (MK421), a new inhibitor of angiotensin converting enzyme, in single daily
doses of 1.25-40 mg was assessed in five patients with hypertension and renal artery …

Enalapril (MK421) in the treatment of hypertension with renal artery stenosis.

GP Hodsman, JJ Brown, AM Cumming… - … : official journal of the …, 1983 - europepmc.org
The converting enzyme inhibitor, enalapril, was given to 20 hypertensive patients with renal
artery stenosis in a single daily dose of 10-40 mg. Enalapril effectively controlled …

Enalapril in the treatment of hypertension with renal artery stenosis.

GP Hodsman, JJ Brown, AM Cumming, DL Davies… - Br Med J (Clin Res …, 1983 - bmj.com
The converting enzyme inhibitor enalapril, in single daily doses of 10-40 mg, was given to
20 hypertensive patients with renal artery stenosis. The blood pressure fall six hours after …

The angiotensin converting enzyme inhibitor enalapril and its effects on renal function.

D de Zeeuw, GJ Navis, AJ Donker… - Journal of hypertension …, 1983 - europepmc.org
The renal effects of the new angiotensin converting enzyme inhibitor enalapril (MK-421) and
of its active metabolite MK-422, were investigated in patients with essential hypertension …

Enalapril in treatment of hypertension with renal artery stenosis: changes in blood pressure, renin, angiotensin I and II, renal function, and body composition

GP Hodsman, JJ Brown, AMM Cumming… - The American journal of …, 1984 - Elsevier
The converting enzyme inhibitor enalapril, in single daily doses of 10 to 40 mg, was given to
20 hypertensive patients with renal artery stenosis. The decrease in blood pressure six …

Non-sulfhydryl-containing angiotensin-converting enzyme inhibitor (MK421): evidence for role of renin system in normotensive subjects.

GA MacGregor, ND Markandu, J Bayliss… - Br Med J (Clin Res …, 1981 - bmj.com
A non-sulfhydryl-containing inhibitor of angiotensin-converting enzyme (MK421) was given
as a single dose in a randomised double-blind cross-over trial using 20 mg and 5 mg of MK …

Use of the converting enzyme inhibitor enalapril in renovascular hypertension. Effect on blood pressure, renal function, and the renin-angiotensin-aldosterone system.

GP Reams, JH Bauer, P Gaddy - Hypertension, 1986 - Am Heart Assoc
Thirteen patients were entered into a protocol to assess the safety and efficacy of enalapril
(MK 421), 5 to 20 mg bid, and hydrochlorothiazide, 50 to 100 mg daily, for the treatment of …

Antihypertensive effect of enalapril as first-step treatment of mild and moderate uncomplicated essential hypertension: evaluation by two methods of blood pressure …

P Sassano, G Chatellier, F Alhenc-Gelas… - The American Journal of …, 1984 - Elsevier
The new angiotensin converting enzyme inhibitor enalapril (MK421), was given in a single
daily dose of 20 mg to 53 patients with uncomplicated essential hypertension. Its effects …

Humoral and renal effects of MK-421 (enalapril) in hypertensive subjects

PW De Leeuw, R Hoogma… - Journal of …, 1983 - journals.lww.com
To assess the effect of MK-421 (enalapril) we treated six hospitalized hypertensive patients
receiving constant sodium intake with incremental doses of this new angiotensin-converting …

Hemodynamic and antihypertensive effects of the new oral angiotensin-converting-enzyme inhibitor MK-421 (enalapril).

FM Fouad, RC Tarazi, EL Bravo, SC Textor - Hypertension, 1984 - Am Heart Assoc
The antihypertensive, hemodynamic, and humoral effects of the new converting-enzyme
inhibitor enalapril (MK-421) were assessed by sequential studies during 3 months of …