In Alzheimer's disease (AD), oxidative stress is present early and contributes to disease
pathogenesis. We previously reported that in Tg19959 transgenic AD mice, partial …

Alzheimer's disease is a multifactorial, progressive, age-related neurodegenerative disease.
In familial Alzheimer's disease, Aβ is excessively produced and deposited because of …

A growing body of evidence suggests a relationship between oxidative stress and β‐amyloid
(Aβ) peptide accumulation, a hallmark in the pathogenesis of Alzheimer's disease (AD) …

While oxidative stress has been linked to Alzheimer's disease, the underlying
pathophysiological relationship is unclear. To examine this relationship, we induced …

Alzheimer's disease (AD) is associated with β-amyloid accumulation, oxidative stress and
mitochondrial dysfunction. However, the effects of genetic mutation of AD on oxidative status …

Substantial evidence supports the hypothesis that oxygen free radicals are involved in
various neurodegenerative disorders. To assess the presence of oxidative stress in …

Alzheimer's disease (AD) is associated with accumulations of amyloid-β (Aβ) peptides,
oxidative damage, mitochondrial dysfunction, neurodegeneration, and dementia. The …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by impaired
cognitive function and the deposition of extracellular amyloid plaques and intracellular …

Manganese superoxide dismutase (Mn‐SOD) is a mitochondrial enzyme that converts toxic
O2‐to H2O2. Previous studies have reported that a systemic deficiency in Mn‐SOD causes …

Background Manganese-dependent superoxide dismutase (MnSOD) is a major defense
mechanism against potential cellular damage by reactive oxygen species (ROS). We have …