[PDF][PDF] Drug repurposing in antiviral research: a current scenario

D Mani, A Wadhwani… - Journal of Young …, 2019 - jyoungpharm.org
Better understand the unexplored parts of the drugs you know than the drugs unidentified.
Drug repurposing is a promising, fast and cost-effective method that can overcome …

Drug repurposing approaches to combating viral infections

J Trivedi, M Mohan, SN Byrareddy - Journal of clinical medicine, 2020 - mdpi.com
Development of novel antiviral molecules from the beginning costs an average of
350millionto 2 billion per drug, and the journey from the laboratory to the clinic takes about …

Drug repurposing: A strategy for discovering inhibitors against emerging viral infections

IJ dos Santos Nascimento… - Current Medicinal …, 2021 - ingentaconnect.com
Background: Viral diseases are responsible for several deaths around the world. Over the
past few years, the world has seen several outbreaks caused by viral diseases that, for a …

Drug repurposing: a shortcut to new biological entities

N Rao, T Poojari, C Poojary, R Sande… - Pharmaceutical Chemistry …, 2022 - Springer
Drug repurposing has proved to be an efficient alternative to drug discovery owing to the
facts that it is economical and risk factors being much lower or even negligible as the drug …

Drug repurposing for antivirulence therapy against opportunistic bacterial pathogens

G Rampioni, P Visca, L Leoni… - Emerging Topics in Life …, 2017 - portlandpress.com
Antibiotic resistance is a serious public health concern at the global level. Available
antibiotics have saved millions of lives, but are progressively losing their efficacy against …

Is drug repurposing really the future of drug discovery or is new innovation truly the way forward?

C Gil, A Martinez - Expert opinion on drug discovery, 2021 - Taylor & Francis
Drug discovery process is a costly and time-consuming task. An average of 12–15 years is
required for a drug to be approved [1]. The investment required to get it increases …

Antiviral activity of approved antibacterial, antifungal, antiprotozoal and anthelmintic drugs: chances for drug repurposing for antiviral drug discovery

L Abdulaziz, E Elhadi, EA Abdallah… - Journal of …, 2022 - Taylor & Francis
Drug repurposing process aims to identify new uses for the existing drugs to overcome
traditional de novo drug discovery and development challenges. At the same time, as viral …

Drug repurposing for viral infectious diseases: how far are we?

B Mercorelli, G Palù, A Loregian - Trends in microbiology, 2018 - cell.com
Despite the recent advances in controlling some viral pathogens, most viral infections still
lack specific treatment. Indeed, the need for effective therapeutic strategies to combat 'old' …

Drug repurposing in the chemotherapy of infectious diseases

A Hamid, P Mäser, AB Mahmoud - Molecules, 2024 - mdpi.com
Repurposing is a universal mechanism for innovation, from the evolution of feathers to the
invention of Velcro tape. Repurposing is particularly attractive for drug development, given …

Drug repurposing strategy (DRS): Emerging approach to identify potential therapeutics for treatment of novel coronavirus infection

BM Sahoo, BVV Ravi Kumar, J Sruti… - Frontiers in Molecular …, 2021 - frontiersin.org
Drug repurposing is also termed as drug repositioning or therapeutic switching. This method
is applied to identify the novel therapeutic agents from the existing FDA approved clinically …