Determinants of affinity and specificity in RNA-binding proteins
Highlights•Interactions between RNA and RNA-binding proteins (RBPs) are typified by
diversity.•Many enigmatic RBPs have been reported, but their interactions are poorly …
diversity.•Many enigmatic RBPs have been reported, but their interactions are poorly …
How RNA-binding proteins interact with RNA: molecules and mechanisms
M Corley, MC Burns, GW Yeo - Molecular cell, 2020 - cell.com
RNA-binding proteins (RBPs) comprise a large class of over 2,000 proteins that interact with
transcripts in all manner of RNA-driven processes. The structures and mechanisms that …
transcripts in all manner of RNA-driven processes. The structures and mechanisms that …
RNA–protein interactions
KB Hall - Current opinion in structural biology, 2002 - Elsevier
Recent discoveries have revealed that there is a myriad of RNAs and associated RNA-
binding proteins that spatially and temporally appear in the cells of all organisms. The …
binding proteins that spatially and temporally appear in the cells of all organisms. The …
RNA–protein interactions in vivo: global gets specific
ML Änkö, KM Neugebauer - Trends in biochemical sciences, 2012 - cell.com
RNA-binding proteins (RBPs) impact every process in the cell; they act as splicing and
polyadenylation factors, transport and localization factors, stabilizers and destabilizers …
polyadenylation factors, transport and localization factors, stabilizers and destabilizers …
A brave new world of RNA-binding proteins
RNA-binding proteins (RBPs) are typically thought of as proteins that bind RNA through one
or multiple globular RNA-binding domains (RBDs) and change the fate or function of the …
or multiple globular RNA-binding domains (RBDs) and change the fate or function of the …
Deciphering the protein‐RNA recognition code: Combining large‐scale quantitative methods with structural biology
RNA binding proteins (RBPs) are key factors for the regulation of gene expression by
binding to cis elements, ie short sequence motifs in RNAs. Recent studies demonstrate that …
binding to cis elements, ie short sequence motifs in RNAs. Recent studies demonstrate that …
Methods to study RNA–protein interactions
Noncoding RNA sequences, including long noncoding RNAs, small nucleolar RNAs, and
untranslated mRNA regions, accomplish many of their diverse functions through direct …
untranslated mRNA regions, accomplish many of their diverse functions through direct …
Integrated structural biology to unravel molecular mechanisms of protein-RNA recognition
A Schlundt, JN Tants, M Sattler - Methods, 2017 - Elsevier
Recent advances in RNA sequencing technologies have greatly expanded our knowledge
of the RNA landscape in cells, often with spatiotemporal resolution. These techniques …
of the RNA landscape in cells, often with spatiotemporal resolution. These techniques …
High-throughput characterization of protein–RNA interactions
RNA-binding proteins (RBPs) are important regulators of eukaryotic gene expression.
Genomes typically encode dozens to hundreds of proteins containing RNA-binding …
Genomes typically encode dozens to hundreds of proteins containing RNA-binding …
Advances in the characterization of RNA‐binding proteins
D Marchese, NS de Groot… - Wiley …, 2016 - Wiley Online Library
From transcription, to transport, storage, and translation, RNA depends on association with
different RNA‐binding proteins (RBPs). Methods based on next‐generation sequencing and …
different RNA‐binding proteins (RBPs). Methods based on next‐generation sequencing and …