[HTML][HTML] FKBP10 regulates protein translation to sustain lung cancer growth
Cancer therapy is limited, in part, by lack of specificity. Thus, identifying molecules that are
selectively expressed by, and relevant for, cancer cells is of paramount medical importance …
selectively expressed by, and relevant for, cancer cells is of paramount medical importance …
[HTML][HTML] FKBP3 promotes proliferation of non-small cell lung cancer cells through regulating Sp1/HDAC2/p27
W Zhu, Z Li, L Xiong, X Yu, X Chen, Q Lin - Theranostics, 2017 - ncbi.nlm.nih.gov
FKBP3 is a member of FK506-binding proteins (FKBPs). Little is known about the expression
and functional role (s) of FKBP3 in non-small cell lung cancer (NSCLC). In the present study …
and functional role (s) of FKBP3 in non-small cell lung cancer (NSCLC). In the present study …
[HTML][HTML] Penetrating exploration of prognostic correlations of the FKBP gene family with lung adenocarcinoma
The complexity of lung adenocarcinoma (LUAD), the development of which involves many
interacting biological processes, makes it difficult to find therapeutic biomarkers for …
interacting biological processes, makes it difficult to find therapeutic biomarkers for …
FKBP4 accelerates malignant progression of non‐small‐cell lung cancer by activating the Akt/mTOR signaling pathway
W Meng, J Meng, H Jiang, X Feng… - Analytical Cellular …, 2020 - Wiley Online Library
Objective. To study the expression, biological function, and mechanism of FKBP4 in non‐
small‐cell lung cancer (NSCLC). Methods. First of all, the expression of FKBP4 in NSCLC …
small‐cell lung cancer (NSCLC). Methods. First of all, the expression of FKBP4 in NSCLC …
[HTML][HTML] FKBP51 induces p53‑dependent apoptosis and enhances drug sensitivity of human non‑small‑cell lung cancer cells
Y Chen, Z Liu, Y Wang, J Zhuang… - Experimental and …, 2020 - spandidos-publications.com
Lung cancer is one of the most prevalent cancer types worldwide, and non‑small‑cell lung
cancer (NSCLC) accounts for~ 85% of all lung cancer cases. Despite the notable …
cancer (NSCLC) accounts for~ 85% of all lung cancer cases. Despite the notable …
[HTML][HTML] Subcellular Expression Patterns of FKBP Prolyl Isomerase 10 (FKBP10) in Colorectal Cancer and Its Clinical Significance
Y Fu, J Chen, X Ma, W Chang, X Zhang, Y Liu… - International Journal of …, 2023 - mdpi.com
FKBP10, a member of the FK506-binding protein (FKBP) family, has been implicated in
cancer development, although its prognostic function remains controversial. In this study, we …
cancer development, although its prognostic function remains controversial. In this study, we …
[HTML][HTML] FKBP10 promotes proliferation of glioma cells via activating AKT-CREB-PCNA axis
HQ Cai, MJ Zhang, ZJ Cheng, J Yu, Q Yuan… - Journal of biomedical …, 2021 - Springer
Background Although the availability of therapeutic options including temozolomide,
radiotherapy and some target agents following neurosurgery, the prognosis of glioma …
radiotherapy and some target agents following neurosurgery, the prognosis of glioma …
[HTML][HTML] FKBP5 as a selection biomarker for gemcitabine and Akt inhibitors in treatment of pancreatic cancer
J Hou, L Wang - PloS one, 2012 - journals.plos.org
We have recently shown that the immunophilin FKBP5 (also known as FKBP51) is a
scaffolding protein that can enhance PHLPP-AKT interaction and facilitate PHLPP-mediated …
scaffolding protein that can enhance PHLPP-AKT interaction and facilitate PHLPP-mediated …
[HTML][HTML] FBXO22 mediates polyubiquitination and inactivation of LKB1 to promote lung cancer cell growth
XN Zhu, P He, L Zhang, S Yang, HL Zhang, D Zhu… - Cell death & …, 2019 - nature.com
Abstract Liver kinase B1 (LKB1) regulates both cell growth and energy metabolism.
Inactivated mutations of LKB1, observed in 20–30% of nonsmall cell lung cancers (NSCLC) …
Inactivated mutations of LKB1, observed in 20–30% of nonsmall cell lung cancers (NSCLC) …
Pleiotropic roles in cancer biology for multifaceted proteins FKBPs
S Romano, A D'Angelillo, MF Romano - Biochimica et Biophysica Acta …, 2015 - Elsevier
Background FK506 binding proteins (FKBP) are multifunctional proteins highly conserved
across the species and abundantly expressed in the cell. In addition to a well-established …
across the species and abundantly expressed in the cell. In addition to a well-established …