The approach to sample acquisition and its impact on the derived human fecal microbiome and VOC metabolome
RD Couch, K Navarro, M Sikaroodi, P Gillevet… - PloS one, 2013 - journals.plos.org
Recent studies have illustrated the importance of the microbiota in maintaining a healthy
state, as well as promoting disease states. The intestinal microbiota exerts its effects …
state, as well as promoting disease states. The intestinal microbiota exerts its effects …
Towards standards for human fecal sample preparation in targeted and untargeted lc-hrms studies
Gut microbiota and their metabolic products are increasingly being recognized as important
modulators of human health. The fecal metabolome provides a functional readout of the …
modulators of human health. The fecal metabolome provides a functional readout of the …
Comparison of fecal collection methods on variation in gut metagenomics and untargeted metabolomics
H Guan, Y Pu, C Liu, T Lou, S Tan, M Kong, Z Sun… - Msphere, 2021 - Am Soc Microbiol
Integrative analysis of high-quality metagenomics and metabolomics data from fecal
samples provides novel clues for the mechanism underpinning gut microbe-human …
samples provides novel clues for the mechanism underpinning gut microbe-human …
Coupling targeted and untargeted mass spectrometry for metabolome-microbiome-wide association studies of human fecal samples
Increasing appreciation of the gut microbiome's role in health motivates understanding the
molecular composition of human feces. To analyze such complex samples, we developed a …
molecular composition of human feces. To analyze such complex samples, we developed a …
Solid-phase microextraction and the human fecal VOC metabolome
E Dixon, C Clubb, S Pittman, L Ammann, Z Rasheed… - PloS one, 2011 - journals.plos.org
The diagnostic potential and health implications of volatile organic compounds (VOCs)
present in human feces has begun to receive considerable attention. Headspace solid …
present in human feces has begun to receive considerable attention. Headspace solid …
Alcohol induced alterations to the human fecal VOC metabolome
RD Couch, A Dailey, F Zaidi, K Navarro, CB Forsyth… - PloS one, 2015 - journals.plos.org
Studies have shown that excessive alcohol consumption impacts the intestinal microbiota
composition, causing disruption of homeostasis (dysbiosis). However, this observed change …
composition, causing disruption of homeostasis (dysbiosis). However, this observed change …
Dual UHPLC-HRMS metabolomics and lipidomics and automated data processing workflow for comprehensive high-throughput gut phenotyping
P Vangeenderhuysen, J Van Arnhem… - Analytical …, 2023 - ACS Publications
In recent years, feces has surfaced as the matrix of choice for investigating the gut
microbiome-health axis because of its non-invasive sampling and the unique reflection it …
microbiome-health axis because of its non-invasive sampling and the unique reflection it …
[PDF][PDF] Optimisation of sample preparation for direct SPME-GC-MS analysis of murine and human faecal volatile organic compounds for metabolomic studies
S Reade, A Mayor, R Aggio, T Khalid… - J Anal Bioanal …, 2014 - researchgate.net
The analysis of volatile organic compounds (VOCs) emitted from biological fluids such as
blood, urine, breath and faeces, has been receiving more attention from researchers and …
blood, urine, breath and faeces, has been receiving more attention from researchers and …
Strategy for Comprehensive Detection and Annotation of Gut Microbiota-Related Metabolites Based on Liquid Chromatography–High-Resolution Mass Spectrometry
S Zheng, W Qin, T Chen, R Ouyang, X Wang… - Analytical …, 2024 - ACS Publications
Gut microbiota, widely populating the mammalian gastrointestinal tract, plays an important
role in regulating diverse pathophysiological processes by producing bioactive molecules …
role in regulating diverse pathophysiological processes by producing bioactive molecules …
Evaluation of fresh, frozen, and lyophilized fecal samples by SPME and derivatization methods using GC× GC-TOFMS
SL Nam, K Tarazona Carrillo, AP de la Mata… - Metabolomics, 2022 - Springer
Introduction Feces is a highly complex matrix containing thousands of metabolites. It also
contains live bacteria and enzymes, and does not have a static chemistry. Consequently …
contains live bacteria and enzymes, and does not have a static chemistry. Consequently …