Objective—There has been accumulating evidence demonstrating that activators for
peroxisome proliferator-activated receptor α (PPARα) have antiinflammatory …

OBJECTIVE: Peroxisome proliferator-activated receptors alpha (PPARα) is a target gene for
atherosclerosis and cardiovascular diseases. However, effects of PPARα on endothelial …

Objective—Peroxisome proliferator-activated receptor γ (PPARγ) ligands reduce lesion
formation in animal models of atherosclerosis by mechanisms that have not been defined …

Recently, peroxisome proliferator-activated receptor γ (PPARγ) ligands have been reported
to increase endothelial NO, but the signaling mechanisms involved are unknown. Using …

Objective—We recently reported that the peroxisome proliferator-activated receptor γ
(PPARγ) ligands 15-deoxy-Δ12, 14-prostaglandin J2 (15d-PGJ2) and ciglitazone increased …

Vascular endothelial cells express the ligand-activated transcription factor, peroxisome
proliferator-activated receptor-γ (PPARγ), which participates in the regulation of metabolism …

Increasing evidence shows that activation of peroxisome proliferator-activated receptors
(PPARs) plays an essential role in the regulation of vascular endothelial function through a …

Peroxisome proliferator–activated receptor-γ (PPARγ) is a key player in glucose metabolism.
If PPARγ ligands modulate nitric oxide (NO) synthesis in the vascular tissue, they may affect …

Background—Peroxisome proliferator–activated receptor (PPAR) signaling pathways have
been reported to exert anti-inflammatory effects and attenuate atherosclerosis formation …

Both nitric oxide (NO·) and peroxisome proliferator‐activated receptors (PPARs) protect the
endothelium and regulate its function. Here, we tested for crosstalk between these signaling …