De novo biosynthesis of 2ʹ‐fucosyllactose by bioengineered Corynebacterium glutamicum

YG Lee, HY Jo, DH Lee, JW Yoon… - Biotechnology …, 2024 - Wiley Online Library
Abstract 2ʹ‐Fucosyllactose (2ʹ‐FL) which is well‐known human milk oligosaccharide was
biotechnologically synthesized using engineered Corynebacterium glutamicum, a GRAS …

Whole cell biosynthesis of a functional oligosaccharide, 2′-fucosyllactose, using engineered Escherichia coli

WH Lee, P Pathanibul, J Quarterman, JH Jo… - Microbial Cell …, 2012 - Springer
Abstract Background 2'-Fucosyllactose (2-FL) is a functional oligosaccharide present in
human milk which protects against the infection of enteric pathogens. Because 2-FL can be …

Biochemical characterization of a novel α-L-fucosidase from Pedobacter sp. and its application in synthesis of 3′-fucosyllactose and 2′-fucosyllactose

R Shi, J Ma, Q Yan, S Yang, Z Fan, Z Jiang - Applied Microbiology and …, 2020 - Springer
Fucosyllactoses have gained much attention owing to their multiple functions, including
prebiotic, immune, gut, and cognition benefits. In this study, human milk oligosaccharide …

Biosynthesis of the human milk oligosaccharide 3‐fucosyllactose in metabolically engineered Escherichia coli via the salvage pathway through increasing GTP …

YH Choi, BS Park, JH Seo… - Biotechnology and …, 2019 - Wiley Online Library
Fucosyllactose (3‐FL) is one of the major fucosylated oligosaccharides in human milk. Along
with 2′‐fucosyllactose (2′‐FL), it is known for its prebiotic, immunomodulator, neonatal …

Production of a human milk oligosaccharide 2′-fucosyllactose by metabolically engineered Saccharomyces cerevisiae

S Yu, JJ Liu, EJ Yun, S Kwak, KH Kim, YS Jin - Microbial Cell Factories, 2018 - Springer
Abstract Background 2′-Fucosyllactose (2-FL), one of the most abundant oligosaccharides
in human milk, has potential applications in foods due to its health benefits such as the …

Synthesis of 2′-fucosyllactose from apple pomace–derived xyloglucan oligosaccharides by an α-L-fucosidase from Pedobacter sp. CAU209

R Shi, S Yang, N Wang, Q Yan, X Yan… - Applied Microbiology and …, 2023 - Springer
Fucosyllactose (2′-FL) is known for its ability to provide various health benefits to infants,
such as gut maturation, pathogen resistance, improved immunity, and nervous system …

[引用][C] 双歧杆菌和乳酸菌β-半乳糖苷酶转糖基作用的研究进展

姜陈波, 杭锋 - 食品科学, 2019

[图书][B] Production of a functional human milk oligosaccharide, 2'-fucosyllactose, using microbial cell factories

P Pathanibul - 2015 - search.proquest.com
Human breast milk is the gold standard for infant nutrition. In human milk, the
oligosaccharides may protect babies by acting as decoy receptors for pathogens. Also …

双歧杆菌对母乳低聚糖利用的研究进展

何竹筠, 杨波, 赵建新, 张灏, 陈卫 - 中国微生态学杂志, 2021 - cjm.dmu.edu.cn
母乳低聚糖(human milk oligosaccharides, HMOs) 是一类存在于人乳中复杂的混合低聚糖,
是母乳中的重要成分, 在婴幼儿生长发育中起到重要作用. 母乳低聚糖可作为影响肠道微生物群 …

Enhanced 2′-Fucosyllactose production by engineered Saccharomyces cerevisiae using xylose as a co-substrate

JW Lee, S Kwak, JJ Liu, S Yu, EJ Yun, DH Kim… - Metabolic …, 2020 - Elsevier
Fucosyllactose (2′-FL), a human milk oligosaccharide with confirmed benefits for infant
health, is a promising infant formula ingredient. Although Escherichia coli, Saccharomyces …