In vitro pro- and anti-inflammatory responses to viable Candida albicans yeasts by a murine macrophage cell line

A Sarazin, D Poulain, T Jouault - Medical Mycology, 2010 - academic.oup.com
The balance between pro-and anti-inflammatory cytokine production is a crucial aspect of
infections caused by Candida albicans. We therefore investigated the effect of yeast …

Candida albicans-infected oral epithelial cells augment the anti-fungal activity of human neutrophils in vitro

A Dongari-Bagtzoglou, CC Villar… - Medical mycology, 2005 - academic.oup.com
Oropharyngeal candidiasis (OPC) is the most common opportunistic infection in
immunosuppressed patients. In OPC, Candida albicans persists intraepithelially triggering …

Absence of functional TLR4 impairs response of macrophages after Candida albicans infection

TH Gasparoto, V Tessarolli, TP Garlet… - Medical …, 2010 - academic.oup.com
Candida albicans is recognized by phagocytic cells through a set of recognition receptors
patterns. Recently, we showed the importance of TLR2 in the regulation of neutrophil …

Absence of TLR2 influences survival of neutrophils after infection with Candida albicans

V Tessarolli, TH Gasparoto, HR Lima… - Medical …, 2010 - academic.oup.com
Candida albicans is an opportunistic pathogen, which causes local and/or disseminated
diseases in immunosuppressed humans. Phagocytic cells play a critical role in the immune …

[HTML][HTML] Candida albicans Induces Selective Development of Macrophages and Monocyte Derived Dendritic Cells by a TLR2 Dependent Signalling

A Yanez, J Megias, JE O'Connor, D Gozalbo, ML Gil - PLoS One, 2011 - journals.plos.org
As TLRs are expressed by haematopoietic stem and progenitor cells (HSPCs), these
receptors may play a role in haematopoiesis in response to pathogens during infection. We …

Candida albicans escapes from mouse neutrophils

D Ermert, MJ Niemiec, M Röhm… - Journal of leukocyte …, 2013 - academic.oup.com
Candida albicans, the most commonly isolated human fungal pathogen, is able to grow as
budding yeasts or filamentous forms, such as hyphae. The ability to switch morphology has …

Both CD4+ and CD8+ lymphocytes reduce the severity of tissue lesions in murine systemic candidiasis, and CD4+ cells also demonstrate strain-specific …

RB Ashman, A Fulurija, JM Papadimitriou - Microbiology, 1999 - microbiologyresearch.org
The role of T lymphocytes in host responses to sublethal systemic infection with Candida
albicans was evaluated by mAb depletion of CD4+ and CD8+ cells from BALB/c and …

[HTML][HTML] Infection of human oral epithelia with Candida species induces cytokine expression correlated to the degree of virulence

M Schaller, CA Sander, HC Korting… - Journal of investigative …, 2002 - Elsevier
A defined and balanced immunomodulatory response is crucial for the protection of mucosal
surfaces being in contact with pathogenic microorganisms. This study examined the local …

Early activation of the interleukin‐23–17 axis in a murine model of oropharyngeal candidiasis

JM Saunus, SA Wagner, MA Matias… - Molecular oral …, 2010 - Wiley Online Library
Candida albicans is an oral commensal yeast that causes oropharyngeal candidiasis (OPC)
in immunocompromised individuals. The immunological pathways involved in OPC have …

Evidence for macrophage-mediated protection against lethal Candida albicans infection

F Bistoni, A Vecchiarelli, E Cenci, P Puccetti… - Infection and …, 1986 - Am Soc Microbiol
Systemic infection of mice with a Candida albicans strain (PCA-2) incapable of yeast-
mycelial conversion conferred protection against a subsequent intravenous challenge with …