The role of CD4+ lymphocytes in resistance of N: NIH (S) III bg/bg nu/+ mice to mucosal
candidiasis was evaluated. Alimentary tract colonization with a pure culture of Candida …

Background and Objective Elderly people exhibit increased susceptibility to a number of
autoimmune and infectious diseases, such as periodontitis. Although aging is reportedly …

Periodontal disease is a chronic inflammatory condition that results in the destruction of the
teeth supporting tissues, eventually leading to the loss of teeth and reduced quality of life. In …

The prevalence of periodontal disease increases with age. Systemic inflammatory
dysregulation also increases with age and has been reported to contribute to the myriad of …

Candida albicans is a dimorphic fungus capable of transition from the yeast form (Y-
Candida) to the hyphal form (H-Candida). Both Y-Candida and H-Candida are known to be …

Intravenous inoculation of an attenuated agerminative strain of Candida albicans (PCA-2) of
low virulence, but not of two other species of Candida of low virulence (C. parapsilosis and …

The defense mechanisms against Candida albicans infection were studied by using a
mouse thigh lesion model in congenitally athymic nude (nu/nu) mice and their normal …

The mechanisms through which Candida albicans is recognized by immune cells and how it
triggers host defence are not completely understood. In this study, we evaluated the effect of …

Candida albicans fungemia in cancer patients is thought to develop from initial
gastrointestinal (GI) colonization with subsequent translocation into the bloodstream after …

Production of reactive oxygen species (ROS) is an important aspect of phagocyte-mediated
host responses. Since phagocytes play a crucial role in the host response to Candida …