Human papillomavirus and oropharynx cancer: biology, detection and clinical implications

CT Allen, JS Lewis Jr, SK El‐Mofty… - The …, 2010 - Wiley Online Library
Objectives: To review evidence for the role of human papillomavirus (HPV) in the etiology of
oropharyngeal cancers, methods of viral detection, and the resulting clinical implications …

Human papillomavirus in oropharyngeal cancer: The changing face of a disease

J Mallen-St Clair, M Alani, MB Wang… - Biochimica et Biophysica …, 2016 - Elsevier
The last decade has brought about an unexpected rise in oropharyngeal squamous cell
carcinoma (OPSCC) primarily in white males from the ages of 40–55 years, with limited …

[HTML][HTML] Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review

RSR Woods, EM O'Regan, S Kennedy… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Human papillomavirus (HPV) has been implicated in the pathogenesis of a subset of
oropharyngeal squamous cell carcinoma. As a result, traditional paradigms in relation to the …

[HTML][HTML] HPV-driven oropharyngeal cancer: current knowledge of molecular biology and mechanisms of carcinogenesis

C Pan, N Issaeva, WG Yarbrough - Cancers of the head & neck, 2018 - Springer
Understanding of oropharyngeal squamous cell carcinoma has significantly progressed
over the last decades, and the concept that this disease can be subdivided into two distinct …

The role of human papillomavirus in oropharyngeal squamous cell carcinoma

BS Ducatman - Archives of pathology & laboratory …, 2018 - meridian.allenpress.com
Context.—Human papillomavirus (HPV) is implicated in the development of oropharyngeal
squamous cell carcinomas (OPC), particularly those cancers developing in tonsillar tissue …

Impact of human papillomavirus on oropharyngeal cancer biology and response to therapy: implications for treatment

J Bonilla-Velez, EA Mroz, RJ Hammon… - … Clinics of North …, 2013 - oto.theclinics.com
Within the recent epidemic of oropharyngeal squamous cell carcinoma (OPSCC), 1 human
papillomavirus (HPV) has been found to play a pivotal role in defining a subset of patients …

[HTML][HTML] Human papillomavirus-related oropharyngeal cancer

M Taberna, M Mena, MA Pavón, L Alemany… - Annals of …, 2017 - Elsevier
High-risk human papillomavirus (HPV) is now recognised as the principal cause of the
increasing incidence rates of oropharyngeal squamous cell carcinoma (OPSCC) in some …

Human papillomavirus and cancer of the oropharynx: Molecular interaction and clinical implications

JP Klussmann, SF Preuss, EJ Speel - Hno, 2009 - Springer
One-third of the cases of oropharyngeal squamous cell carcinoma (OSCC) contain
oncogenic human papillomavirus (HR-HPV). Epidemiologic and molecular evidence …

Molecular mechanisms of HPV induced carcinogenesis in head and neck

T Rampias, C Sasaki, A Psyrri - Oral oncology, 2014 - Elsevier
A growing subgroup of oropharyngeal cancers is initiated by infection with high-risk human
papillomaviruses (HPVs). In parallel to mounting epidemiological evidence, solid …

Biology of human papillomavirus–related oropharyngeal cancer

JD Howard, CH Chung - Seminars in radiation oncology, 2012 - Elsevier
Recent data show that human papillomavirus–positive oropharyngeal cancer (OPC) has a
distinct biological and clinical behavior compared with human papillomavirus–negative …