In recent years, neurological diseases including Alzheimer's disease, Parkinson's disease
and stroke are one of the main causes of death in the world. At the same time, the incidence …

Background Magnolia officinalis, a traditional herbal medicine widely used in clinical
practice, exerts antibacterial, anti-tumor, anti-inflammatory, antioxidant, and anti-aging …

Honokiol is a neolignan biphenol found in aerial parts of the Magnolia plant species. The
Magnolia plant species traditionally belong to China and have been used for centuries to …

Magnolol and honokiol are natural lignans with good physiological effects. As the main
active substances derived from Magnolia officinalis, their pharmacological activities have …

Today, neurological disorders such as epilepsy, depression, tardive dyskinesia, and stress,
and neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease …

Background Cognitive deficit is the main clinical feature of Alzheimer's disease (AD), and the
massive death of neuronal cells is the leading cause of cognitive deficits. So, there is an …

Developed regions, including Japan, have become “aged societies,” and the number of
adults with senile dementias, such as Alzheimer's disease (AD), Parkinson's disease, and …

In the course of screening for neuroprotective natural products, Magnoliae Cortex showed
potent inhibition of hippocampal neuronal HT22 cell death. Obovatol, honokiol, and …

Background The bark of magnolia has been used in Oriental medicine to treat a variety of
remedies, including some neurological disorders. Magnolol (Mag) and honokiol (Hon) are …

Objectives The exposure of neurons to an excessive excitatory stimulation induces the
alteration of the normal neuronal function. Mood disorders are among the first signs of …