Impact on outcomes of mixed chimerism of bone marrow CD34+ sorted cells after matched or haploidentical allogeneic stem cell transplantation for myeloid …

Y Le Bris, D Costes, R Bourgade, T Guillaume… - Bone Marrow …, 2022 - nature.com
Allogeneic hematopoietic stem cell transplantation (Allo-HSCT), proposed to patients with
high-risk myeloid malignancies, may ultimately fail because of disease relapse. Bone …

[HTML][HTML] Peripheral Blood CD34+ Donor Chimerism Is Superior to CD3+ Donor Chimerism for Predicting Relapse Following Allogeneic Stem Cell Transplantation for …

T Das, D North, S Fleming, D Kliman, A Spencer… - Blood, 2020 - Elsevier
Background: Disease relapse remains the main cause of mortality after allogeneic stem cell
transplantation (allo-SCT) for patients with myeloid malignancies. Loss of donor chimerism …

[HTML][HTML] Long-Term Mixed Chimerism After Ex Vivo/In Vivo T Cell-Depleted Allogeneic Hematopoietic Cell Transplantation in Patients With Myeloid Neoplasms

L Ruhnke, F Stölzel, U Oelschlägel, M von Bonin… - Frontiers in …, 2021 - frontiersin.org
In patients who have undergone allogeneic hematopoietic cell transplantation (HCT),
myeloid mixed donor chimerism (MC) is a risk factor for disease relapse. In contrast, several …

Serial quantification of lymphoid and myeloid mixed chimerism using multiplex PCR amplification of short tandem repeat-markers predicts graft rejection and relapse …

F Fernandez-Aviles, A Urbano-Ispizua, M Aymerich… - Leukemia, 2003 - nature.com
We used multiplex amplification of nine microsatellite sequences (PCR-STR) to analyse
chimerism in pure populations of T cells and neutrophils from peripheral blood from 40 …

[HTML][HTML] Systematic comparison of donor chimerism in peripheral blood and bone marrow after hematopoietic stem cell transplantation

C Bach, M Steffen, W Roesler, J Winkler… - Blood Cancer …, 2017 - nature.com
Incomplete donor chimerism (DC) after hematopoietic stem cell transplantation (HSCT) is
associated with reduced overall and disease-free survival and decreasing DC can precede …

[HTML][HTML] Does early chimerism testing predict outcomes after allogeneic hematopoietic stem cell transplantation?

L Mountjoy, J Palmer, KL Kunze, N Khera… - Leukemia & …, 2021 - Taylor & Francis
Allogenic stem cell transplantation (HCT) is a potentially curative treatment for patients with
various hematologic malignancies. Following HCT it is common practice to assess …

Utility of assessing CD3+ cell chimerism within the first months after allogeneic hematopoietic stem‐cell transplantation for acute myeloid leukemia

M Bendjelloul, C Usureau, P Etancelin, Z Saidak… - Hla, 2022 - Wiley Online Library
After allogeneic hematopoietic stem‐cell transplantation (alloHSCT), the chimerism assay is
used to monitor cell engraftment and quantify the respective proportions of donor/recipient …

Mixed chimerism of bone marrow CD34+ progenitor cells (genotyping, bcr/abl analysis) after allogeneic transplantation for chronic myelogenous leukemia1

J Thiele, C Wickenhauser, HM Kvasnicka… - …, 2002 - journals.lww.com
Background. Although CD34+ progenitors play a crucial role during bone marrow
transplantation (BMT), there is only scant knowledge concerning their lineage-restricted …

Very early lineage-specific chimerism after reduced intensity stem cell transplantation is highly predictive of clinical outcome for patients with myeloid disease

FAM Kinsella, CF Inman, A Gudger, YT Chan… - Leukemia research, 2019 - Elsevier
Background The importance of chimerism status in the very early period after hematopoietic
stem cell transplantation is unclear. We determined PBMC and T-cell donor chimerism 50 …

[HTML][HTML] Early Mixed T-Cell Chimerism After Allogeneic Hematopoietic Stem Cells Transplantation Is Highly Predictive For Progression Free Survival

J Cornillon, L Absi, A Bourmaud, M Srour, F Tinquaut… - Blood, 2013 - Elsevier
Introduction Chimerism analysis after allogeneic hematopoietic stem cells transplantation
(HSCT) allows documentation and understanding of important clinical events such as …