The development of erythrocyte alloantibodies complicates transfusion therapy in β
thalassemia major patients. These antibodies increase the need for blood and intensify …

The development of hemolytic erythrocyte alloantibodies and autoantibodies complicates
transfusion therapy in thalassemia patients. These antibodies ultimately increase the need …

Background Red blood cell (RBC) alloimmunization is a major challenge to repeated
transfusions in β-thalassemia-major patients. The aim of this study was to evaluate the …

Objective We aimed to find out the frequency of alloimmunization in multitransfused β-
thalassemic patients, the most common alloantibodies involved, factors contributing to their …

Background: The development of hemolytic alloantibodies and erythrocyte autoantibodies
complicates transfusion therapy in thalassemia patients. Methods: The frequency, causes …

Materials and Methods: This prospective, cross-sectional study was conducted at the
Department of Blood Transfusion Services and Thalassemia Centre of Pakistan Institute of …

SUMMARY Background In Pakistan routine blood group typing of thalassemia patients
identifies ABO and Rh (D) antigens only. Therefore, other antigen incompatibilities between …

BACKGROUND β‐Thalassemia is considered the most common chronic hemolytic anemia
in Egypt. Alloimmunization can lead to serious clinical complications in transfusion …

Background: The development of anti-red blood cell antibodies (both allo-and
autoantibodies) remains a major problem in thalassemia major patients. We studied the …

Abstract Background and Objective: The mainstay of management of severe β-thalassemia
remains lifelong blood transfusion. The development of one or more alloantibody against …