Volatomics in inflammatory bowel disease and irritable bowel syndrome

K Van Malderen, BY De Winter, G Joris… - …, 2020 - thelancet.com
Volatile organic compounds (VOCs) are produced by the human metabolism, inflammation
and gut microbiota and form the basis of innovative volatomics research. VOCs detected …

Extending landscape of volatile metabolites as novel diagnostic biomarkers of inflammatory bowel disease–a review

I Ahmed, F Fayyaz, M Nasir, Z Niaz… - Scandinavian Journal …, 2016 - Taylor & Francis
The diagnosis of inflammatory bowel disease (IBD) remains a challenging task despite
significant increase in the understanding of the disease aetiology and pathogenesis. Recent …

Investigation of faecal volatile organic metabolites as novel diagnostic biomarkers in inflammatory bowel disease

I Ahmed, R Greenwood, B Costello… - Alimentary …, 2016 - Wiley Online Library
Background The aetiology of inflammatory bowel disease (IBD) remains poorly understood.
Recent evidence suggests an important role of gut microbial dysbiosis in IBD, and this may …

Volatile organic compounds as potential biomarkers of irritable bowel syndrome: A systematic review

VRY Zhang, GK Ramachandran… - …, 2023 - Wiley Online Library
Background Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disease
characterized by intermittent abdominal pain with altered bowel habits. Due to the …

Fecal volatile organic compounds: a novel, cheaper method of diagnosing inflammatory bowel disease?

CSJ Probert, S Reade, I Ahmed - Expert Review of Clinical …, 2014 - Taylor & Francis
The investigation of a novel, cheaper method of diagnosing inflammatory bowel disease
(IBD) is an area of active research. Recently, investigations into the metabolomic profile of …

Volatile organic compound profiling as a potential biomarker in irritable bowel syndrome: A feasibility study

K Van Malderen, N Hanning, H Lambrechts… - Frontiers in …, 2022 - frontiersin.org
Background Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder for which
no diagnostic tools are currently available. Patients are diagnosed using the Rome IV …

Diagnosing Inflammatory bowel disease using noninvasive applications of volatile organic compounds: A systematic review

AS Bannaga, A Farrugia… - Expert Review of …, 2019 - Taylor & Francis
Introduction: Inflammatory bowel disease (IBD) is a common disease with significant
morbidity. Noninvasive diagnostic techniques are lacking in IBD. Currently, fecal calprotectin …

Volatile organic compounds in breath as markers for irritable bowel syndrome: a metabolomic approach

A Baranska, Z Mujagic, A Smolinska… - Alimentary …, 2016 - Wiley Online Library
Background The diagnosis of irritable bowel syndrome (IBS) is challenging because of its
heterogeneity and multifactorial pathophysiology. No reliable biomarkers of IBS have been …

[HTML][HTML] Non-invasive exhaled volatile organic biomarker analysis to detect inflammatory bowel disease (IBD)

RP Arasaradnam, M McFarlane, E Daulton… - Digestive and Liver …, 2016 - Elsevier
Introduction Early inflammatory bowel disease (IBD) diagnosis remains a clinical challenge.
Volatile organic compounds (VOCs) have shown distinct patterns in Crohn's disease (CD) …

Application of fecal volatile organic compound analysis in clinical practice: Current state and future perspectives

S El Manouni el Hassani, DJC Berkhout, S Bosch… - Chemosensors, 2018 - mdpi.com
Increasing interest is noticed in the potential of volatile organic compound (VOC) analysis as
non-invasive diagnostic biomarker in clinical medical practice. The spectrum of VOCs …