[HTML][HTML] Single-cell transcriptome atlas of murine endothelial cells
The heterogeneity of endothelial cells (ECs) across tissues remains incompletely
inventoried. We constructed an atlas of> 32,000 single-EC transcriptomes from 11 mouse …
inventoried. We constructed an atlas of> 32,000 single-EC transcriptomes from 11 mouse …
Single-cell RNA sequencing unveils unique transcriptomic signatures of organ-specific endothelial cells
Background: Endothelial cells (ECs) display considerable functional heterogeneity
depending on the vessel and tissue in which they are located. Whereas these functional …
depending on the vessel and tissue in which they are located. Whereas these functional …
Endothelial cell diversity revealed by global expression profiling
The vascular system is locally specialized to accommodate widely varying blood flow and
pressure and the distinct needs of individual tissues. The endothelial cells (ECs) that line the …
pressure and the distinct needs of individual tissues. The endothelial cells (ECs) that line the …
Single-cell analysis of the normal mouse aorta reveals functionally distinct endothelial cell populations
Background: The cells that form the arterial wall contribute to multiple vascular diseases.
The extent of cellular heterogeneity within these populations has not been fully …
The extent of cellular heterogeneity within these populations has not been fully …
Single cell analysis of endothelial cells identified organ-specific molecular signatures and heart-specific cell populations and molecular features
Endothelial cells line the inner surface of vasculature and play an important role in normal
physiology and disease progression. Although most tissue is known to have a …
physiology and disease progression. Although most tissue is known to have a …
Integrated single-cell atlas of endothelial cells of the human lung
Background: Cellular diversity of the lung endothelium has not been systematically
characterized in humans. We provide a reference atlas of human lung endothelial cells …
characterized in humans. We provide a reference atlas of human lung endothelial cells …
Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration
DJ Nolan, M Ginsberg, E Israely, B Palikuqi… - Developmental cell, 2013 - cell.com
Microvascular endothelial cells (ECs) within different tissues are endowed with distinct but
as yet unrecognized structural, phenotypic, and functional attributes. We devised EC …
as yet unrecognized structural, phenotypic, and functional attributes. We devised EC …
Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation
Blood vessels are lined by endothelial cells engaged in distinct organ-specific functions but
little is known about their characteristic gene expression profiles. RNA-Sequencing of the …
little is known about their characteristic gene expression profiles. RNA-Sequencing of the …
Deciphering endothelial heterogeneity in health and disease at single-cell resolution: progress and perspectives
LM Becker, SH Chen, J Rodor… - Cardiovascular …, 2023 - academic.oup.com
Endothelial cells (ECs) constitute the inner lining of vascular beds in mammals and are
crucial for homeostatic regulation of blood vessel physiology, but also play a key role in …
crucial for homeostatic regulation of blood vessel physiology, but also play a key role in …
Human organ-specific endothelial cell heterogeneity
The endothelium first forms in the blood islands in the extra-embryonic yolk sac and then
throughout the embryo to establish circulatory networks that further acquire organ-specific …
throughout the embryo to establish circulatory networks that further acquire organ-specific …