Biodegradable electrospun fibers for drug delivery

J Zeng, X Xu, X Chen, Q Liang, X Bian, L Yang… - Journal of controlled …, 2003 - Elsevier
The influences of surfactants and medical drugs on the diameter size and uniformity of
electrospun poly (l-lactic acid)(PLLA) fibers were examined by adding various surfactants …

Influence of the drug compatibility with polymer solution on the release kinetics of electrospun fiber formulation

J Zeng, L Yang, Q Liang, X Zhang, H Guan, X Xu… - Journal of controlled …, 2005 - Elsevier
The electrospun fiber mat for drug delivery is a novel formulation with promising clinical
applications in the future. The influence of the solubility and compatibility of drugs in the …

Coaxial Electrospun Poly(L‐Lactic Acid) Ultrafine Fibers for Sustained Drug Delivery

CL He, ZM Huang, XJ Han, L Liu… - … Science, Part B, 2006 - Taylor & Francis
A coaxial electrospinning technique to fabricate core‐shell ultrafine fiber mats for drug
delivery application is described in this paper. Poly (l‐lactic acid)(PLLA) and tetracycline …

Controlled dual release of hydrophobic and hydrophilic drugs from electrospun poly (l-lactic acid) fiber mats loaded with chitosan microspheres

J Xu, Y Jiao, X Shao, C Zhou - Materials letters, 2011 - Elsevier
This work is to develop novel electrospun poly (l-lactic acid)(PLLA) fiber mats for controllable
delivery of hydrophobic and hydrophilic drugs. For this aim, bovine serum albumin (BSA …

Ultrafine fibers electrospun from biodegradable polymers

J Zeng, X Chen, X Xu, Q Liang, X Bian… - Journal of Applied …, 2003 - Wiley Online Library
Abstract Biodegradable poly (l‐lactide)(PLLA) and poly (ε‐caprolactone)(PCL) were
electrospun into ultrafine fibers. The technological parameters influencing the spinning …

Electrospun poly(D,L‐lactide) fibers for drug delivery: The influence of cosolvent and the mechanism of drug release

Z Xie, G Buschle‐Diller - Journal of Applied Polymer Science, 2010 - Wiley Online Library
Controlled‐drug release from electrospun fibers has found important biomedical
applications in wound healing, transdermal delivery, and tissue engineering. In this study …

Release of antibiotics from electrospun bicomponent fibers

G Buschle-Diller, J Cooper, Z Xie, Y Wu, J Waldrup… - Cellulose, 2007 - Springer
Biocompatible nanofibers that are capable of adapting to the physiological conditions of the
human body have become increasingly important for clinical applications in recent years …

The influence of fiber diameter of electrospun poly (lactic acid) on drug delivery

SC Chen, XB Huang, XM Cai, J Lu, J Yuan, J Shen - Fibers and Polymers, 2012 - Springer
Electrospinning is a simple process for the production of fibers with diameters in the range
from submicron to micron. Herein we aim to explore the influence of fibrous diameter on the …

Controlled protein release from electrospun biodegradable fiber mesh composed of poly (ɛ-caprolactone) and poly (ethylene oxide)

TG Kim, DS Lee, TG Park - International journal of pharmaceutics, 2007 - Elsevier
A blend mixture of poly (ɛ-caprolactone)(PCL) and poly (ethylene oxide)(PEO) was
electrospun to produce fibrous meshes that could release a protein drug in a controlled …

Investigation of Drug Release and Matrix Degradation of Electrospun Poly(dl-lactide) Fibers with Paracetanol Inoculation

W Cui, X Li, X Zhu, G Yu, S Zhou, J Weng - Biomacromolecules, 2006 - ACS Publications
This study was aimed at assessing the potential use of electrospun fibers as drug delivery
vehicles with focus on the different diameters and drug contents to control drug release and …