Oogenesis involves complex differentiation program leading to the production of functional
oocytes. Oogonia originating from primordial germ cells proliferate by mitosis and form …

Abstract Development of the female oocyte is a unique process involving mitosis, meiosis,
cell cycle arrest, and activation and maturation of the cytoplasm of a single cell. These …

Successful fertilization and early development depend on the quality of the ovulated oocyte.
Our knowledge lacks of links between morphological aspects described and the genomic …

Folliculogenesis is a complex process requiring both extragonadal and intragonadal factors
aimed at the production of fully mature oocytes, ready to be fertilized. The follicle is the …

The oocyte is one of the largest and most mysterious of cells in mammalian organisms. After
many years of inactivity in a primordial state, the oocyte progresses through growth and …

The oocyte is a unique and highly specialized cell responsible for creating, activating, and
controlling the embryonic genome, as well as supporting basic processes such as cellular …

Genetic, endocrine, physiological, anatomical, and immunological abnormalities of the
reproductive system can affect a woman's likelihood of becoming pregnant and delivering a …

The processes that encompass oocyte maturation are essential for the formation of haploid
mature eggs capable to undergo the critical transition from gamete to embryo upon …

Early embryonic development of the human oocyte, as for the oocytes of all mammalian
species, is under the control of the maternally inherited genome. It is not until the 4-to 8-cell …

Successful human reproduction requires gamete maturation, fertilization, and early
embryonic development. Human oocyte maturation includes nuclear and cytoplasmic …