Functional nutrition is a valuable supplementation to dietary therapy. Functional foods are
enriched with biologically active substances. Plant polyphenols attract particular attention …

Polyphenols extracted from grape seeds are able to inhibit amyloid-beta (Aβ) aggregation,
reduce Aβ production and protect against Aβ neurotoxicity in vitro. We aimed to investigate …

Dietary supplements such as grape seed extract (GSE) enriched in proanthocyanidins
(PA)(oligomeric polyphenols) have been suggested to have multiple health benefits, due to …

Introduction: Gradual population aging is creating a new set of needs in the general
population. Memory capacity decreases with age, and memory deficits are considered an …

The development of effective medicines to break or delay the progressive brain
degeneration underlying cognitive decline and dementia that characterize Alzheimer's …

Dementia contributes substantially to the burden of disability experienced at old age, and
mitochondrial dysfunction (MD) was identified as common final pathway in brain aging and …

Parkinson's disease (PD) is a progressive neurodegenerative disorder that is characterized
by a loss of dopaminergic neurons, leading to bradykinesia, rigidity, tremor at rest, and …

Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common age-related
neurodegenerative disorders and hence pose remarkable socio-economical burdens to …

No effective preventive treatment is available for age-related cognitive decline and
Alzheimer's disease (AD). Epidemiological studies indicate that a diet rich in fruit is …

Research in animals and humans has indicated that polyphenols can delay the age-related
decline in learning, memory and neurodegenerative diseases. Among the polyphenols …