The potentiation of cardiodepressant and hypotensive effects of bradykinin by enalapril and captopril both in vitro and in vivo

M Prostran, R Samardžić, Z Todorović… - … : The Vascular System, 1991 - Elsevier
Bradykinin (cumulative concentrations of 0.007-0.09 μ g ml− 1) produced a dose-related, but
statistically insignificant depression of the isometric contraction of the isolated …

[PDF][PDF] THE EFFECTS OF BRADYKININ AND BRADYKININ ANTAGONISTS ON THE ISOLATED RAT HEART.

RA Tio, E Scholtens, WH van Gilst… - The cardiac effects of …, 1992 - research.rug.nl
Summary 1 The effects of bradykinin on coronary flow, left ventricular pressure, rate
pressure product and heart rate were investigated in the isolated rat heart. 2 In the isolated …

Influence of endogenous bradykinin on acute blood pressure response to vasopressors in normotensive rats assessed with a bradykinin antagonist

JF Aubert, B Waeber, J Nussberger… - Journal of …, 1988 - journals.lww.com
The present study was designed to assess in conscious normotensive rats the influence of
various pressor agents on the acute blood pressure response to a bradykinin antagonist …

[引用][C] The systemic and coronary hemodynamic effects of synthetic bradykinin

GG Rowe, S Afonso, CA Castillo, F Lioy, JE Lugo… - American Heart …, 1963 - Elsevier
The systemic and coronary hemodynamic effects of bradykinin have been studied during its
infusion into anesthetized dogs. 2. The administration of bradykinin is associated with …

Role of endogenous bradykinins in the acute depressor effect of angiotensin converting enzyme inhibitor captopril—Assessed by a competitive antagonist of …

M Seino, K Abe, N Nushiro, K Omata… - … Hypertension. Part A …, 1989 - Taylor & Francis
To examine whether a hypotensive effect of converting enzyme inhibitor captopril was
mediated partly by a potentiation of endogenous bradykinin, a newly synthesized …

[PDF][PDF] Interaction of bradykinin and angiotensin in the regulation of blood pressure in conscious rats

M Van Den Buuse, J Kerkhoff - General Pharmacology: The Vascular …, 1991 - academia.edu
1. The interaction between bradykinin (BK) and the renin-angiotensin system was studied in
conscious, catheterized rats. 2. Intravenous injection of BK induced dose-dependent …

Effect of bradykinin on arteries and veins in systemic and pulmonary circulation

G Bönner, S Preis, U Schunk, M Wagmann… - Journal of …, 1992 - journals.lww.com
Bradykinin is a potent vasodilating and natriuretic peptide, which is potentiated by
angiotensin-converting enzyme (ACE) inhibitors. In our investigations we studied the effect …

Lack of a role of circulating bradykinin in the blood pressure response to acute angiotensin converting enzyme inhibition in rats.

JF Aubert, B Waeber, J Nussberger… - Agents and actions …, 1987 - europepmc.org
The role of circulating bradykinin in blood pressure regulation was investigated in conscious
normotensive rats using a competitive antagonist of bradykinin. The acute blood pressure …

Importance of sympathetic innervation in the positive inotropic effects of bradykinin and ramiprilat.

RD Minshall, VP Yelamanchi, A Djokovic… - Circulation …, 1994 - Am Heart Assoc
Isolated rat left atria or right ventricular strips were electrically stimulated at a constant
frequency. The amplitude of twitch contractions, thus elicited, rose as a function of …

FAILURE OF ENDOGENOUS BLOOD KININ LEVELS ELEVATED BY CAPTOPRIL TO INDUCE HYPOTENSION IN NORMOTENSIVE AND HYPERTENSIVE RATS: A …

M MAJIMA, M KATORI, M OGINO, M SAITO… - Biomedical …, 1996 - jstage.jst.go.jp
ABSTRACT Captopril (10 mg/kg, ip) increased the arterial bradykinin (BK) level of non-
treated Sprague-Dawley rats, determined by a newly developed ELISA, from 10.8 i 3.2 pg/ml …