Human contact with the nontuberculous mycobacteria (NTM) is quite common, yet serious
infections with these organisms were relatively infrequent until the advent of AIDS …

Studies of patients with severe infections arising from poorly pathogenic mycobacterium or
Salmonella species have revealed genetic mutations in type-1 cytokine (IL-12p40) or type-1 …

Interleukin (IL)-12/IL-23 signal transduction-deficient individuals with genetic defects in
IL12RB1 or IL12B often suffer from unusual mycobacterial and Salmonella infections. Here …

Inborn errors of human interferon gamma (IFN-γ) immunity underlie mycobacterial disease.
We report a patient with mycobacterial disease due to inherited deficiency of the …

Mendelian susceptibility to mycobacterial disease (MSMD) is a rare condition characterized
by predisposition to clinical disease caused by weakly virulent mycobacteria, such as BCG …

Genetic and population studies suggest that onset, progression and ultimate outcome of
infection with Mycobacteria, including the agent of tuberculosis Mycobacterium tuberculosis …

In this review, we discuss the role of cytokines and their signaling pathways in
immunodeficiency. We focus primarily on severe combined immunodeficiency (SCID) …

Natural human immunity to the mycobacteria group, including Mycobacterium tuberculosis,
Bacille Calmette-Guérin (BCG) or nontuberculous mycobacteria (NTM), and/or Salmonella …

Since 1996, several studies characterizing the association between primary
immunodeficiencies and susceptibility to infections with environmental and non-pathogenic …

The interferon‐(IFN‐) γ expression is elicited in response to microbial infections and
activates immune surveillance by antimicrobial immune elements to induce microbial killing …