The sounds of silence have forever been broken as genetics and genomics approaches in
human and model organisms have provided a powerful and rapid entry into gene discovery …

The study of hereditary hearing impairments provides a unique opportunity to deal with two
objectives simultaneously:(i) identification of the causative genes and the underlying …

Nearly all genes that have been localized for autosomal dominantly inherited hearing
impairment are characterized by postlingual hearing loss that is progressive in nature. This …

Hearing loss (HL) is the most common sensory impairment and is caused by a broad range
of inherited to environmental causes. Inherited HL consists 50–60% of all HL cases. The …

Over the last decade, we have seen a tremendous growth in the localisation and
identification of genes for nonsyndromic hearing impairment. It has become clear that this …

Congenital hearing loss (hearing loss that is present at birth) is one of the most prevalent
chronic conditions in children. In the majority of developed countries, neonatal hearing …

As auditory genes and deafness-associated mutations are discovered at a rapid rate,
exciting opportunities have arisen to uncover the molecular mechanisms underlying hearing …

Objectives: We sought to elucidate the gene expression profiles of the causative genes as
well as the localization of the encoded proteins involved in hereditary hearing loss. Methods …

Hearing loss is a common and complex condition that can occur at any age, can be inherited
or acquired, and is associated with a remarkably wide array of etiologies. The diverse …

From the first identified non-syndromic hearing loss gene in 1995, to those discovered in
present day, the field of human genetics has witnessed an unparalleled revolution that …