Multiple sclerosis (MS) is the most important autoimmune disease of the central nervous
system (CNS). Its animal model experimental autoimmune encephalomyelitis (EAE) has …

Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis
(EAE), are autoimmune demyelinating diseases of the central nervous system (CNS) …

Th17 cells and their proinflammatory signature cytokine, IL-17, have recently replaced Th1
cells to be the essential Th effector population in autoimmune disease. This was based on a …

The discovery of the T helper (Th) 17 lineage, involved in the protection against fungal and
extracellular bacterial infections, has profoundly revolutionized our current understanding of …

It has been firmly established that IL-23 polarized TH17 cells are potent effectors in the
pathogenesis of experimental autoimmune encephalitomyelitis (EAE). However, the relative …

It has recently been proposed that experimental autoimmune encephalomyelitis, once
considered the classical Th1 disease, is predominantly Th17 driven. In this study we show …

Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis
(MS) that shares many features with the human disease. This review will focus on the role of …

T helper (Th) 17 cells are responsible for host defense against fungi and certain extracellular
bacteria but have also been reported to play a role in a variety of autoimmune diseases …

Multiple sclerosis (MS) is an autoimmune disease characterized by recurrent episodes of
demyelination and axonal lesion mediated by CD4+ T cells with a proinflammatory Th1 and …

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …