Urban dust particulate matter alters PAH-induced carcinogenesis by inhibition of CYP1A1 and CYP1B1
LA Courter, T Musafia-Jeknic, K Fischer… - Toxicological …, 2007 - academic.oup.com
The polycyclic aromatic hydrocarbons (PAHs) benzo [a] pyrene (B [a] P) and dibenzo [a, l]
pyrene (DB [a, l] P) are well-studied environmental carcinogens, however, their potency …
pyrene (DB [a, l] P) are well-studied environmental carcinogens, however, their potency …
Altered gene expression patterns in MCF-7 cells induced by the urban dust particulate complex mixture standard reference material 1649a
B Mahadevan, C Keshava, T Musafia-Jeknic, A Pecaj… - Cancer research, 2005 - AACR
Human exposures to polycyclic aromatic hydrocarbon (PAH) occur in complex mixtures.
Here, gene expression patterns were investigated using standard reference material (SRM) …
Here, gene expression patterns were investigated using standard reference material (SRM) …
Long-term effects of a standardized complex mixture of urban dust particulate on the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons in human …
T Musafia-Jeknic, B Mahadevan, C Pereira… - Toxicological …, 2005 - academic.oup.com
Humans are exposed to complex mixtures of polycyclic aromatic hydrocarbons in the
atmosphere. We examined the long term effects of a standard reference material (SRM) …
atmosphere. We examined the long term effects of a standard reference material (SRM) …
Activation of the aryl hydrocarbon receptor is the major toxic mode of action of an organic extract of a reference urban dust particulate matter mixture: the role of …
Z Andrysík, J Vondráček, S Marvanová… - Mutation Research …, 2011 - Elsevier
Many of the toxic and carcinogenic effects of urban air pollution have been linked to
polycyclic aromatic hydrocarbons (PAHs) adsorbed to airborne particulate matter (PM). The …
polycyclic aromatic hydrocarbons (PAHs) adsorbed to airborne particulate matter (PM). The …
Aryl hydrocarbon receptor plays a significant role in mediating airborne particulate-induced carcinogenesis in mice
Y Matsumoto, F Ide, R Kishi, T Akutagawa… - … science & technology, 2007 - ACS Publications
Urban particulate air pollution is associated with an increased incidence of cancers, and
especially lung cancer. Organic extracts of airborne particulate matter (APM) cause cancer …
especially lung cancer. Organic extracts of airborne particulate matter (APM) cause cancer …
Genotoxic potential of polycyclic aromatic hydrocarbons-coated onto airborne particulate matter (PM2. 5) in human lung epithelial A549 cells
S Billet, I Abbas, J Le Goff, A Verdin, V André… - Cancer Letters, 2008 - Elsevier
To improve the knowledge of the underlying mechanisms of action involved in air pollution
Particulate Matter (PM)-induced toxicity in human lungs, with a particular interest of the …
Particulate Matter (PM)-induced toxicity in human lungs, with a particular interest of the …
The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo
LA Courter, A Luch, T Musafia-Jeknic, VM Arlt… - Cancer letters, 2008 - Elsevier
The carcinogenic effects of individual polycyclic aromatic hydrocarbons (PAH) are well
established. However, their potency within an environmental complex mixture is uncertain …
established. However, their potency within an environmental complex mixture is uncertain …
Oxidative damage induced by carcinogenic polycyclic aromatic hydrocarbons and organic extracts from urban air particulate matter
K Hanzalova, P Rossner Jr, RJ Sram - Mutation Research/Genetic …, 2010 - Elsevier
We investigated the role of oxidative damage in the mechanism of action of selected
individual carcinogenic PAHs (c-PAHs: benzo [a] pyrene, B [a] P; dibenzo [a, l] pyrene, DB …
individual carcinogenic PAHs (c-PAHs: benzo [a] pyrene, B [a] P; dibenzo [a, l] pyrene, DB …
Cytotoxicity and genotoxicity of urban particulate matter in mammalian cells
AF Dumax-Vorzet, M Tate, R Walmsley, RH Elder… - …, 2015 - academic.oup.com
Ambient air particulate matter (PM)-associated reactive oxygen species (ROS) have been
linked to a variety of altered cellular outcomes. In this study, three different PM samples from …
linked to a variety of altered cellular outcomes. In this study, three different PM samples from …
[HTML][HTML] Environmentally prevalent polycyclic aromatic hydrocarbons can elicit co-carcinogenic properties in an in vitro murine lung epithelial cell model
AK Bauer, K Velmurugan, S Plöttner, KJ Siegrist… - Archives of …, 2018 - Springer
Low molecular weight (LMW) polycyclic aromatic hydrocarbons (PAH) are the most
abundant PAHs environmentally, occupationally, and are in cigarette smoke; however, little …
abundant PAHs environmentally, occupationally, and are in cigarette smoke; however, little …