Abstract Background Short tandem repeats (STRs) compose approximately 3% of the
genome, and mutations at STR loci have been linked to dozens of human diseases …

Abstract Microsatellites, or Short Tandem Repeats (STRs), are subject to frequent length
mutations that involve the loss or gain of an integer number of repeats. This work aimed to …

Short tandem repeats (STRs) are some of the fastest mutating loci in the genome. Tools for
accurately profiling STRs from high-throughput sequencing data have enabled genome …

A tandem repeat's (TR) propensity to mutate increases with repeat number, and can become
very pronounced beyond a critical boundary, transforming it into a microsatellite (MS) …

Short tandem repeats (STRs) are mutation-prone loci that span nearly 1% of the human
genome. Previous studies have estimated the mutation rates of highly polymorphic STRs by …

Short tandem repeats (STRs) are hyper-mutable sequences in the human genome. They are
often used in forensics and population genetics and are also the underlying cause of many …

Background Screening for short tandem repeat (STR) expansions in next-generation
sequencing data can enable diagnosis, optimal clinical management/treatment, and …

Short tandem repeats (STRs) are highly polymorphic sequences throughout the human
genome that are composed of repeated copies of a 1–6-bp motif. Over 1 million variable …

Short tandem repeats (STRs) are consecutive repetitions of one to six nucleotide motifs.
They are hypervariable due to the high prevalence of repeat unit insertions or deletions …

Short Tandem Repeats (STRs) have been found to play a role in a myriad of complex traits
and genetic diseases. We examined the variability in the lengths of over 850,000 STR loci in …